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Glaucoma Research and Clinical Advances
Foreword Volume 2 of our serial publication continues our desire to address glaucoma with a combination of science and speculation. As science expands, the emphasis is on data, interpretation, and dogma. We disagree; open minds open new approaches. Using methodologies that are primarily molecular and genetic, we seek to refine the causes of glaucoma as well as how it is best treated, especially incorporating thoughts and hypotheses about new methods of treatment. Glaucoma is a complex disease, and genetics proves that a variety of proteins are culpable at one level. At another level, however, there are likely final common pathways and numerous feedback loops which have defied explanations to...
Ocular Blood Flow in Glaucoma
This is the sixth World Glaucoma Association Consensus. The relationship between ocular blood flow and glaucoma has been discussed for more than a century, and still it uniformly fuels debates at glaucoma meetings throughout the world. Clearly, the results of this report will have broad and significant impact on glaucoma research and clinical practice. The global faculty, consisting of leading authorities on the scientific and clinical aspects of ocular blood flow, have met in Fort Lauderdale on May 2, 2009 to discuss the reports and refine the consensus statements.
Biosimilars and Generic Medications in Ophthalmology
In this book, the authors present the history of generic drug development, FDA and European Medecines Agency (EMA) requirements for generic drug entry, a comparison of generic and branded drugs, concerns around generic ophthalmic drugs, the issues of costs of generic and branded drugs, and issues as well as perceptions regarding the clinical use and acceptance of generic drugs among the patients, prescribers, and pharmacists. In addition to the previous edition, a chapter has been added about biosimilars.
Vascular Considerations in Glaucoma
Preface Open angle glaucoma (OAG) is one of the leading causes of impaired vision worldwide. The pathogenesis of glaucomatous optic neuropathy remains poorly understood, and several pathogenic mechanisms are proposed to coexist. As the world population ages, OAG will become more prevalent and advances in the diagnosis and treatment of glaucomatous optic neuropathy are important to protect and improve the quality of life of our aging population. Treatment of OAG has been directed at lowering intraocular pressure (IOP) which is the only current therapeutic strategy available to patients with glaucoma. While a wide variety of studies have demonstrated that lowering IOP decreases the risk of gla...
Intraocular and Intracranial Pressure Gradient in Glaucoma
This book focuses on the characteristic of glaucomatous optic neuropathy and its relationship with cerebrospinal fluid (CSF) pressure. It also explores the potential novel methods to manage glaucoma by adjusting CSF pressure. This book covers several interesting topics such as why normal tension glaucoma (NTG) patients still develops into glaucoma without high intraocular pressure (IOP); and whether there are factors other than IOP contributing to the pathogenesis of NTG why the role of IOP in the pathogenesis of POAG becomes vague and controversial. This book contains over 40 chapters, including numerous images from clinical patients and experiments on gross anatomy, pathological tissue, and immunohistochemistry, electronic speculum etc. The ophthalmologists and researchers can also benefit from the clinical cases. We hope this book serves as a clinical guidance with practical significant for the understanding, prevention and diagnosis of glaucoma.
Nano-Biomaterials For Ophthalmic Drug Delivery
This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of na...
Atlas of Glaucoma, Third Edition
Glaucoma affects all age groups and is a leading cause of blindness worldwide. It is imperative that practicing clinicians and surgeons recognize both primary and secondary glaucoma as well as cases of glaucoma associated with other disorders. Atlas of Glaucoma, Third Edition provides an in-depth review and analysis of the management of glaucoma and discusses research advancements that have resulted in the latest therapies. See What's New in the Third Edition: The influence of the cornea on intraocular pressure measurements and new devices designed to account for this Spectral domain optical coherence tomography (OCT) New statistical methods for tracking rates of progression New medications ...
Color Atlas and Synopsis of Clinical Ophthalmology -- Wills Eye Institute -- Glaucoma
This text is part of the Color Atlas and Synopsis of Clinical Ophthalmology which was developed at Philadelphia’s famed Wills Eye Institute. The beauty of this series is the powerful combination of illustrative photographs and a summary approach to the text. While the seven ophthalmic subspecialties in this series, Cornea, Retina, Glaucoma, Oculoplastics, Neuroophthalmology, Pediatrics, and Uveitis, employ varying levels of visual recognition, a relatively standard format for the text is used for all volumes. The goal of the series is to provide an up-to-date clinical overview of the major areas of ophthalmology for students, residents, and practitioners in all the healthcare professions. ...
Current Developments in Glaucoma Surgery and MIGS
Successful interventional glaucoma remains a sought-after goal for the glaucoma clinician for many reasons. Medical costs, compliance, and adherence remain major barriers for the treatment of our patients. A truly definitive treatment for glaucoma is most likely to be largely surgical, as it is doubtful that patients will continue to use glaucoma drugs in the future for anything other than transient lowering of intraocular pressure. In the coming era, it seems probable that neuroprotection and neurorestoration will be combined with MIGS to lower pressure. The different types of MIGS are increasing in proportion to their efficacy. To date, there are no fewer than 12 choices available to glaucoma specialists. Choice of procedure depends on the underlying anatomy as well as the patient’s individual characteristics. Truthfully, the number of available surgeries depends upon their taxonomy. Most are based on the outflow system and the canal, as illustrated in this book.
Advances in Ophthalmology and Optometry, E-Book 2021
Advances in Ophthalmology and Optometry reviews the most current practices in both ophthalmology and optometry. A distinguished editorial board, headed by Dr. Myron Yanoff, identifies key areas of major progress and controversy and invites expert ophthalmologists and optometrists to contribute original articles devoted to these topics. Broken into sections, this sixth volume in the series covers topics within each of the following categories: Optometry, Cataracts, Pediatrics, Ophthalmic Pathology & Ocular Oncology, Vitreoretinal Disease, Glaucoma, Neuro-ophthalmology, Oculoplastics, and Uveitis.
