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This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and c...
Principle of Reinforced Concrete introduces the main properties of structural concrete and its mechanical behavior under various conditions as well as all aspects of the combined function of reinforcement and concrete. Based on the experimental investigation, the variation regularity of mechanical behavior, working mechanism, and calculation method are presented for the structural member under various internal forces. After examining the basic principle and analysis method of reinforced concrete, the book covers some extreme circumstances, including fatigue load, earthquake, explosion, high temperature (fire accident), and durability damage, and the special responses and analysis methods of ...
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color figures, and are presented in a lucid style.
Reports on recent advances in detecting drugs, hormones, antibodies, and other molecules of diagnostic importance; research has been going on in such fields as dentistry, clinical chemistry, and steroid hormones, but the researchers have not been talking to each across the disciplinary back fence. A
Excerpt from Aetiology of Tuberculosis Dr. Koch's treatise on the AEtiology of Tubercolosis, has been translated with the authorization of the author, and is presented to the medical and veterinary professions of the United States as the most remarkable work on the subject. It is reprinted from the American Veterinary Review, and the translation is due to the Massachusetts State Veterinary Medical Association, who recognized its importance and undertook the labor of the work. The present edition is due to the demand for the treatise in its entirety, and although it is issued without the illustrations of the costly German edition, it will be found of the greatest advantage to all investigatio...
Combining insights from both cognitive neuroscience and molecular biology, two of the world's leading experts address memory from molecules and cells to brain systems and cognition. What is memory and where in the brain is it stored? How is memory storage accomplished? This book touches on these questions and many more, showing how the recent convergence of psychology and biology has resulted in an exciting new synthesis of knowledge about learning and remembering. Memory: From Mind to Molecules is an ideal primer for courses on learning and memory or for general readers who are interested in discovering what is currently known about one of the basic aspects of human existence.
"Professor Felice Jacka is filling the huge gap that exists in both psychiatric and psychological training. This book changed the way I thought about the significance of nutrition, both personally and for my clients. Everyone needs access to this education about how their own brain works." DR JULIE SMITH "This is a fascinating book by a leading researcher, covering one of the most exciting areas of modern nutritional research about how our diet can impact our gut and brain health. The combination of personal stories and cutting-edge science is a real winner" DR MICHAEL MOSLEY, AUTHOR AND TV PRESENTER A combination of Professor Felice Jacka's love of food and her own experience of depression ...
Learn how to make your .NET applications secure! Security and cryptography, while always an essential part of the computing industry, have seen their importance increase greatly in the last several years. Microsoft's .NET Framework provides developers with a powerful new set of tools to make their applications secure. NET Security and Cryptography is a practical and comprehensive guide to implementing both the security and the cryptography features found in the .NET platform. The authors provide numerous clear and focused examples in both C# and Visual Basic .NET, as well as detailed commentary on how the code works. They cover topics in a logical sequence and context, where they are most re...
More than 12,000 years ago, in one of the greatest triumphs of prehistory, humans colonized North America, a continent that was then truly a new world. Just when and how they did so has been one of the most perplexing and controversial questions in archaeology. This dazzling, cutting-edge synthesis, written for a wide audience by an archaeologist who has long been at the center of these debates, tells the scientific story of the first Americans: where they came from, when they arrived, and how they met the challenges of moving across the vast, unknown landscapes of Ice Age North America. David J. Meltzer pulls together the latest ideas from archaeology, geology, linguistics, skeletal biology...