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Crucibles
Classic popular account of the great chemists Trevisan, Paracelsus, Avogadro, Mendeléeff, the Curies, Thomson, Lavoisier, and others, up to A-bomb research and recent work with subatomic particles. 20 illustrations.
β-Carbolines
β-Carbolines: A Privileged Scaffold for Modern Drug Discovery provides a summary of methods for the synthesis of various natural products engineered with the diverse β-carboline scaffold and their biological evaluation. β-carboline and its derivatives have generated considerable interest in recent years for their versatile properties in chemistry and pharmacology. This is due to their ability to act as agonists to benzodiazepine receptors, hydroxy serotonin receptors, and intercalate into DNA and to inhibit CDK, topisomerase, and monoamine oxidase enzymes. Their pharmacological properties include anxiolytic, hypnotic, anticonvulsant, antiviral, antiparasitic, and antimicrobial attributes....
Total Chemical Synthesis of Proteins
How to synthesize native and modified proteins in the test tube With contributions from a panel of experts representing a range of disciplines, Total Chemical Synthesis of Proteins presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins. Comprehensive in scope, this important reference explores the three main chemoselective ligation methods for assembling unprotected peptide segments, including native chemical ligation (NCL). It includes information on synthetic strategies for the complex polypeptides that constitute glycoproteins, sulfoproteins, and membrane proteins, as well as their characterization. In additio...
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Organic Chemistry in Medicine
This book is intended for students in medicine, pharmacy, and dentistry, physicians, dentists, pharmacists, biochemists, and more. It describes organic compounds that are of importance for medicine: heterocycles, alkaloids, carbohydrates, lipids, proteins, enzymes, nucleic acids, and more. Organic chemistry plays a pivotal role in medicine and in developing, synthesizing, and understanding pharmaceutical compounds. It focuses on carbon-containing compounds, which form the backbone of organic molecules. Functional groups within organic molecules modulate the biochemical properties of organic compounds, like stability, solubility, and activity. Organic chemistry is used for designing drug formulations based on disease mechanisms. Short biographies of chemists and scientists, which have rendered services to general and inorganic chemistry in medicine, are given in a person index.
General and Inorganic Chemistry in Medicine
This book is intended for students in medicine, pharmacy, and dentistry, physicians, dentists, pharmacists, biochemists, and more. In General Chemistry, the laws of chemistry, the structure of simple and complex compounds, chemical bonds, solutions, chemical reactions, kinetics, equilibrium, thermodynamics, protolytic and redox processes, and sorption are discussed. In Inorganic Chemistry, chemical elements, inorganic compounds, and their significance for medicine are presented. It is focused on developing metal-based diagnostic and therapeutic agents. The significance of coordination chemistry to modulate enzyme activity is discussed. The production of reactive oxygen species selectively damaging cancer cells is described, too. Short biographies of chemists and scientists, which have rendered services to general and inorganic chemistry in medicine, are given in a person index.
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