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Pharmaceutics is very pleased to be hosting a Special Issue in honor of Dr. Marie-Hélène Metz-Boutigue, acknowledging her influential scientific contributions to research on Antimicrobial Peptides (AMPs). This Special Issue aimed to gather and highlight significant advancements for AMPs as an alternative to antibiotics for increasing resistant strains and recent discoveries for future therapeutic approaches. Since the AMPs are multifunctional peptides with antitumor and immunomodulating effects, original research articles and reviews in these fields were particularly welcomed. Manuscripts regarding antimicrobial biomaterials including AMPs were also of interest.
Oral glucocorticoids are potent anti-inflammatory and immunosuppressant agents used to treat and control several conditions. However, oral glucocorticoid exposure leads to an osteoporotic state characterized by increased bone loss and fracture risk. Bone loss is rapid upon oral glucocorticoid exposure, particularly in the vertebra. Osteoporosis treatment are often recommended for patients receiving oral glucocorticoids to prevent fracture. However, osteoporosis drug benefit in randomized controlled trials and observational studies is not yet established among oral glucocorticoid users. This research aimed to estimate fracture rates among new and ongoing oral glucocorticoid users and assess t...
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Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for indiv...