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Plastic and Reconstructive Surgery in Personalized Medicine
Plastic and reconstructive surgery has a broad spectrum of different reconstructive techniques, including split skin transplantation and local and free flaps. By means of microsurgery and perforator flaps, every reconstructive issue can be addressed by tailored techniques. Flaps can comprise different tissues and can be designed using new imaging technologies in order to increase the safety of the procedures and to retain the form and function of the reconstructed area in accordance with the donor site morbidity. This Special Issue of the Journal of Personalized Medicine focuses on the following topics: Individualized microsurgery; Flap imaging; Customized perforator flaps; Monitoring flap perfusion; Tailored tissue engineering for reconstruction; Biofabrication applications in personalized plastic and reconstructive surgery.
Deep Sternal Wound Infections
This concise and practical handbook covers the basics of pathophysiology, diagnosis, interdisciplinary surgical management, prevention and rehabilitation of patients with deep sternal wound infections and sternal osteomyelitis. All relevant aspects and surgical procedures are explained in an easily understandable way. Additionally special approaches and preventive measures are highlighted with regard to the perioperative handling as well as the rehabilitation possibilities. Through concise texts with numerous illustrations, the book is ideal for the practice and as a supplement to further studies. This book is suitable for all specialists who are involved into the treatment and diagnosis of sternal wound infections, particularly cardio-thoracis, thoracic, plastic, vascular surgeons, cardiologists, radiologists, and rehabilitation physicians.
Telocytes
This book elucidates the genetic, biological, morphological and functional aspects of telocytes. Telocytes are a recently defined type of interstitial (stromal) cells, with very long (tens to hundreds of micrometres) and very thin prolongations (mostly below the resolving power of light microscopy). The book describes the presence of telocytes in various organs and tissues, details their morphological characteristics, explores their genomic and proteomic profiles, puts forward preclinical evidence of their application, and discusses their potential in the context of clinical therapeutics. As such, it offers a valuable guide for biologists and clinicians alike. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of the Shanghai Institute of Clinical Bioinformatics, Executive Director of the Clinical Science Institute at Fudan University Zhongshan Hospital, Shanghai, China; Dr. Dragos Cretoiu is an Associate Professor of Pathology at the Department of Cellular and Molecular Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest.
Handbook of Burns Volume 2
The second edition of this volume has been updated with chapters on scar treatment using laser, microneedling, tissue engineering, adipose tissue and lipofilling. It compiles the perspectives of a multi-author team, examining the entire spectrum of burn reconstruction and long-term treatment. Individual updated chapters cover basic aspects of wound healing and scarring, and plastic surgery relating to tissue rearrangement and the use of flaps, as well as the long-term use of skin and skin substitutes. Furthermore, it addresses topics such as rehabilitation and scar management in detail. It provides comprehensive reconstruction guidelines organized by anatomic region (e.g. face, hands, ...) as well as future trends and prospects in burn reconstruction, such as allotransplantation and bionics. Please also have a look at the volume "Handbook of Burns Volume 1 - Acute Burn Care 2nd edition"
Lower Gastrointestinal Tract Surgery
This atlas, containing a wealth of clear operative images, is designed to enable trainee surgeons to visualise the surgical field for procedures specific to open colorectal surgery, thereby facilitating understanding and learning of surgical techniques and avoidance of intra- and postoperative complications. Step-by-step guidance is provided for a wide range of procedures to the colon, rectum, pelvic floor, anus and anal canal, in each case paying meticulous attention to surgical anatomy. The full range of potential indications for open surgery is considered, including benign and malignant tumours, inflammatory bowel disease, appendicitis, diverticulitis, hemorrhoids, anal fistulas and rectal prolapse among others. Whenever considered necessary, additional line drawings are included to aid comprehension of particular steps in the surgery. Readers seeking to improve their understanding of surgical anatomy and how to perform these operative procedures will find the atlas to be an unparalleled source of information and assistance. A complementary book from the same authors focuses on laparoscopic colorectal surgery.
Adaptation Biology and Medicine
It has become amply clear that all live forms on Earth are the products of the constituent genes expressed under the influence of continuously changing natural environment. By the same token, gene expression is known to be modified by our (or by the modern) environment inclusive of factors such as gravity, altitude, temperature, atmospheric pressure and air quality, physical conditioning as well as nutrition and/or lifestyle. Life would not survive without recruiting endogenous adaptive mechanisms responsive to challenging environmnetal factors, Biology of adaptation as well as application of this knowledge has been discussed in both health and disease conditions such as cardiac ischemia and cardiomyopathies, stroke, dementia, Alzheimer's, cancer, metal toxicity, etc. The book will be of great interest to experimental biologists and health professionals dealing with benefits and failures of physiological and pathophysiological adaptations. It will also serve as an important source of information for young scientists, postdocs and students.
Plastic Surgery for the Oncological Patient
The develoment of plastic surgery techniques allows for preserving and reconstruction of function after resection of malignant tumors. From split thickness skin grafts to pedicled and free tissue transfer multiple techniques are at hand to restore body integrity. Sufficient soft tissue coverage allows for adjuvant radiation therapy or can cure its sequelae. Nerve, tendon and muscle transfers are used to regain motor function of the extremities. Even large bony defects can be treated by microsurgically transferring fibula, pelvic and femoral bone. In case main vessels need to be resected reconstruction is possible with autologous and artificial grafts. By means of plastic surgery thoracic and...
