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Patient-Specific Modeling of the Cardiovascular System
Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 ...
Biomechanics of Soft Tissue in Cardiovascular Systems
The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.
Analysis of Cardiac Development
This volume, the result of three days of interactive sessions among world leaders in the cardiac sciences, summarizes the most up-to-date information about development and cardiogenesis signaling in cell-based therapy, as well as developmental aspects of the formation of the embryonic heart, including the effect of mechanical load on differentiation. Other topics covered include: signaling and repair strategies, cell and gene therapy for the treatment of postmyocardial infarction, signaling, vascularization methods in engineering embryonic cardiac tissue, and molecular methods to improve survival of human embryonic stem cell–derived cardiomyocytes; developmental and evolutional cardiology;...
Charisma and Patronage
A detailed and richly illustrated analysis of charisma and the political and cultural conditions in which charismatic figures arise, this work of historical sociology critically engages with Max Weber’s ambiguous concept of charisma to examine the charismatic careers of a number of figures, including Joan of Arc, Hitler and Nelson Mandela, as well as that of Jesus, who, the author contends - in contradistinction to Max Weber - was not a charismatic leader, in spite of his portrayal in Christian theology. Shedding light on the process of charismatic transformation as it occurs within intensely solidaristic groups and the importance of patronage in charismatic careers, the book distinguishes...
Functional Imaging and Modeling of the Heart
This book constitutes the refereed proceedings of the First International Workshop on Functional Imaging and Modeling of the Heart, FIMH 2001, held in Helsinki, Finland, in November 2001.The 17 revised full papers presented together with four invited papers were carefully reviewed and selected for inclusion in the book. The papers are organized in topical sections on anatomical modeling, motion and deformation, functional imaging, and towards electromechanical modeling.
A Math Primer for Engineers
Mathematics and engineering are inevitably interrelated, and this interaction will steadily increase as the use of mathematical modelling grows. Although mathematicians and engineers often misunderstand one another, their basic approach is quite similar, as is the historical development of their respective disciplines. The purpose of this Math Primer is to provide a brief introduction to those parts of mathematics which are, or could be, useful in engineering, especially bioengineering. The aim is to summarize the ideas covered in each subject area without going into exhaustive detail. Formulas and equations have not been avoided, but every effort has been made to keep them simple in the hop...
11th Asian-Pacific Conference on Medical and Biological Engineering
This book presents cutting-edge research and developments in the field of medical and biological engineering, which a special emphasis on activities carried out in the Asian-Pacific region. Gathering the proceedings of the 11th Asian-Pacific Conference on Medical and Biological Engineering, organized in Japan and held online on May 25-27, 2020, the book both fundamental research and clinical applications relating to medical instrumentations, bioimaging, bioinformatics and computational biomedicine, AI and data science in healthcare, as well as regenerative medicine and rehabilitation. It aims at informing on new trends, challenges and solutions, and fosters communication and collaboration between medical scientists, engineers, and researchers dealing with cutting-edge themes in broad field of biomedical and clinical engineering.
Computational Physiology
This open access volume compiles student reports from the 2022 Simula Summer School in Computational Physiology. The reports provide an overview of some tools available to model physiology in excitable tissues across scales and scientific questions. In 2022, Simula held the eighth annual Summer School in Computational Physiology in collaboration with the University of Oslo (UiO) and the University of California, San Diego (UCSD). Each year, the course focuses on modeling excitable tissues, with a special interest in cardiac physiology and neuroscience. Group research projects conducted by graduate students from around the world result in reports addressing problems of physiological importance. Reports may not necessarily represent new scientific results; rather, they can reproduce or supplement earlier studies. Reports from seven of the summer projects are included as separate chapters. The topics represented include multiscale mechanics, electrophysiology, pharmacology, and machine learning.
Cardiac Mechano-Electric Coupling and Arrhythmias
Ranging from stretch-activated ion channels to mechanically induced arrhythmias and mechanical interventions for heart rhythm correction, this new edition offers a thoroughly reviewed compendium of chapters, written by the top-experts in the world, on the mechanism and consequences of cardiac mechano-electrical coupling.
Myocardial Laser Revascularization
Finally, there is a dependable guide to transmyocardial laser revasculariztion (TMR). In this groundbreaking volume, clinicians who pioneered the use of this innovative treatment share their insights on the indications, results, mechanisms, and limitations of the technique. Under the careful editorial guidance of Drs. Bridges, Horvath, and Chiu, contributing authors explain: the evolution, science, rationale, and limitations for TMR how to select suitable candidates anesthetic considerations and the role of transesophageal echo TMR as a sole or combination therapy Whether you are already practicing TMR or contemplating its addition to your therapeutic armamentarium, this concise reference will answer all your questions about this important new procedure.
