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Death Cloud
Death Cloud is the first in the Young Sherlock Holmes series in which the iconic detective is reimagined as a brilliant, troubled and engaging teenager – creating unputdownable detective adventures that remain true to the spirit of the original books. The year is 1868, and Sherlock Holmes is fourteen. His life is that of a perfectly ordinary army officer’s son: boarding school, good manners, a classical education – the backbone of the British Empire. But all that is about to change. With his father suddenly posted to India, and his mother mysteriously ‘unwell’, Sherlock is sent to stay with his eccentric uncle and aunt in their vast house in Hampshire. So begins a summer that leads Sherlock to uncover his first murder, a kidnap, corruption and a brilliantly sinister villain of exquisitely malign intent . . . Sherlock Holmes. Think you know him? Think again. Continue the investigative adventures with Andrew Lane's Red Leech and Black Ice.
A Traditional Muʻtazilite Qurʼān Commentary
Based mainly on primary sources and manuscript evidence, this book presents an in-depth study of the life and work of J?r All?h al-Zamakhshar? (d.538/1144). More specifically, it examines the sources and history, contents and method of his Qur n commentary," Kashsh?f,"
Night Break
Sherlock's mother has died, his father has disappeared in India and his sister is acting strangely. The Holmes family seems to be falling apart, and not even brother Mycroft can keep it together. But while Sherlock is worrying about all of this, a man living nearby vanishes in his own house while Sherlock and Mycroft are visiting. Where did he go, and what is the connection with a massive canal being built in Egypt? The answer will rock the world, and tear the Holmes family apart!Another fast-paced, brilliantly plotted adventure in Andrew Lane's Young Sherlock series as the teenage Sherlock Holmes investigates a new crime and comes up against a fresh crop of sinister, clever crooks.
Young Sherlock Holmes: Bedlam (Short Reads)
Young Sherlock Holmes: Bedlam is Andrew Lane's short read in which the iconic detective is reimagined as a brilliant, troubled and engaging teenager. Sherlock has been incarcerated in the Bethlehem Hospital – Bedlam - where Victorian London’s most unfortunate citizens are locked away in squalor, cruelty and hopelessness. Sherlock tells them he’s not mad – but who’d believe a lunatic? There’s only one option: he has to escape – and then use all his rational powers to work out who put him there in the first place . . . Sherlock Holmes: think you know him? Think again.
Black Ice
Black Ice is the third in the Young Sherlock Holmes series in which the iconic detective is reimagined as a brilliant, troubled and engaging teenager – creating unputdownable detective adventures that remain true to the spirit of the original books. The year is 1868, and fourteen-year-old Sherlock Holmes faces his most baffling mystery yet. Mycroft, his older brother, has been found with a knife in his hand, locked in a room with a corpse. Only Sherlock believes that his brother is innocent. But can he prove it? In a chase that will take him to Moscow and back, Sherlock must discover who has framed Mycroft and why . . . before Mycroft swings at the gallows. Sherlock Holmes. Think you know him? Think again. Continue the investigative adventures with Andrew Lane's Fire Storm and Snake Bite.
Biophysical Tools for Biologists
Driven in part by the development of genomics, proteomics, and bioinformatics as new disciplines, there has been a tremendous resurgence of interest in physical methods to investigate macromolecular structure and function in the context of living cells. This volume in Methods in Cell Biology is devoted to biophysical techniques in vitro and their applications to cellular biology. Biophysical Tools for Biologists covers methods-oriented chapters on fundamental as well as cutting-edge techniques in molecular and cellular biophysics. This book is directed toward the broad audience of cell biologists, biophysicists, pharmacologists, and molecular biologists who employ classical and modern biophysical technologies or wish to expand their expertise to include such approaches. It will also interest the biomedical and biotechnology communities for biophysical characterization of drug formulations prior to FDA approval. - Describes techniques in the context of important biological problems - Delineates critical steps and potential pitfalls for each method - Includes full-color plates to illustrate techniques
Sport and Exercise Psychology
The new edition of Sport and Exercise Psychology asks four fundamental questions that get to the heart of this flourishing discipline: What inner states influence what people think, feel, and behave? How can people manage or self-regulate their own inner states? How can sport and exercise psychology professionals help people manage their inner states? Is sport psychology just a placebo effect? Taking an applied perspective that bridges the gap between sport and exercise, the book answers these questions by covering the key topics in the field, including confidence, anxiety, self-regulation, stress and self-esteem. There are also chapters on the role of music in performance, imagery and exercise addiction. Each chapter is written by an expert in that field, and includes a range of features illustrating specific issues, either within the research literature or their practical application. This is a comprehensive and engaging overview of an evolving discipline, and will be essential reading to any student of sport and exercise psychology. It will also be of huge interest to athletes and coaches seeking an accessible understanding of the role of psychology in sport.
Methodologies for Metabolomics
Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.
Comprehensive Systems Biomedicine
Systems Biomedicine is a field in perpetual development. By definition a translational discipline, it emphasizes the role of quantitative systems approaches in biomedicine and aims to offer solutions to many emerging problems characterized by levels and types of complexity and uncertainty unmet before. Many factors, including technological and societal ones, need to be considered. In particular, new technologies are providing researchers with the data deluge whose management and exploitation requires a reinvention of cross-disciplinary team efforts. The advent of “omics” and high-content imaging are examples of advances de facto establishing the necessity of systems approaches. Hypothesi...
