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Polyglutamine Disorders
This book provides a cutting-edge review of polyglutamine disorders. It primarily focuses on two main aspects: (1) the mechanisms underlying the pathologies’ development and progression, and (2) the therapeutic strategies that are currently being explored to stop or delay disease progression. Polyglutamine (polyQ) disorders are a group of inherited neurodegenerative diseases with a fatal outcome that are caused by an abnormal expansion of a coding trinucleotide repeat (CAG), which is then translated in an abnormal protein with an elongated glutamine tract (Q). To date, nine polyQ disorders have been identified and described: dentatorubral-pallidoluysian atrophy (DRPLA); Huntington’s dise...
The Behavioral Neurology of Dementia
Distils the most valuable discoveries in dementia research into clear, insightful chapters written by international experts.
The Challenge of Comparative Literature
In this work, Claudio Guillen meditates on the elusive field of comparative literature and its vicissitudes since the early 19th century.
The Author as Plagiarist
An in-depth look at how Machado de Assis affirms his uniqueness through the role of a reflective reader who eventually becomes a self-reflective author, whose text is primarily the written memory of his private library
Winter_1962_Foreign_Amateur_Callbook
This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Cerebrospinal Fluid Biomarkers
This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.
Filipino Philosophy
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We Stand on the Shoulders of Those Who Came Before Us
The beginning of a legacy to never be forgotten. It is the starting point of who you are. It is the examination of where you come from. Composed of characters, personalities, a climax or two... you know the things that explain why y'all, as a family, think the way y'all think and act the way y'all act. This is your story. Your family's story.
Occupation
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