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Noninvasive Mechanical Ventilation
The new edition presents updates regarding new clinical applications of noninvasive mechanical ventilation and discusses recent technical advances in this field. The opening sections are devoted to theory , equipment, with new chapters on clinical applications in emergency medicine, critical care and sleep medicine, with detailed attention to current studies on NIV-CPAP, innovative clinical implications of NIV-CPAP devices. Due attention is also paid to new ventilation modes and the development of synchronization and patient ventilator interaction results. The closing chapters examine clinical indication. Written by internationally recognized experts in the field, this book will be an invaluable guide for both clinicians and researchers.
High Flow Nasal Cannula
This book presents the state of the art in high-flow nasal cannula (HFNC), an oxygen therapy technique that has recently proven to be a very promising approach to supporting respiratory function in several medical fields. In the opening part of the book, readers will learn the differences between high-flow and low-flow techniques and gain an overview of HFNC’s technical aspects and physiological effects. The book subsequently describes the pathophysiological mechanisms involved in different respiratory diseases, analyzing how this technique positively impacts patients’ respiratory status. The authors highlight clinical applications of HFNC, both in adults and in children, in various clinical settings – e.g. intensive care and semi-intensive care unit, emergencies, rehabilitation etc. – and present tips, tricks and pitfalls, as well as up-to-date reports on technical issues. The book is intended for pneumologists, intensivists, anesthesiologists, ED doctors, rehabilitation therapists, internists and oncologists, as well as fellows and nurses in these fields.
Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications
This book reports the text of the lectures of the 6th International Conference on Sodium Calcium Exchange held in Lacco Ameno in the Island of Ischia in the Gulf of Naples, Italy, from October 1 to October 5, 2011. The present book uncovers the most striking new findings on NCX that emerged since the previous Conference on Sodium Calcium Exchange, such as the structural dissection of the molecular determinants of Ca2+ sensitivity of the exchanger, the epigenetic regulation of ncx1 gene, the molecular identification of the mitochondrial Sodium Calcium Exchanger, and the discovery of NCX in unexpected anatomical locations such as the female reproductive tract. The book is organized into 11 parts covering NCX structural aspects, genetic and epigenetic regulation, regulatory mechanisms, subcellular localization in mitochondria, involvement in neurodegenerative diseases and in immune regulation, and the role of the cardiovascular and endocrine systems, as well as diabetes in physiology and pathophysiology. Selected chapters of the book are also devoted to the interaction of NCKX and other ion channels and transporters with NCX, like ASICs, TRPM, and NHE.
Peroxiporins
To produce energy, aerobic organisms transform oxygen molecules into water. This reductive mechanism yields toxic radical intermediates, collectively known as reactive oxygen species (ROS). Paradoxically, these physiological processes entail the production of potentially damaging species. Evolution has turned this apparent disadvantage into an opportunity for transmitting information. As a result, redox signaling within the cell is an efficient exquisitely organized process. A key element for its regulation is the physical separation of sources and targets into different cell compartments. Peroxiporins, H2O2 transporting proteins spanning biological membranes, distribute the signal from emit...
Mechanical Ventilation E-Book
One of the key tools in effectively managing critical illness is the use of mechanical ventilator support. This essential text helps you navigate this rapidly evolving technology and understand the latest research and treatment modalities. A deeper understanding of the effects of mechanical ventilation will enable you to optimize patient outcomes while reducing the risk of trauma to the lungs and other organ systems. A physiologically-based approach helps you better understand the impact of mechanical ventilation on cytokine levels, lung physiology, and other organ systems. The latest guidelines and protocols help you minimize trauma to the lungs and reduce patient length of stay. Expert con...
Practical Issues Updates in Anesthesia and Intensive Care
This book describes the state of the art concerning some of the most hotly debated topics in anesthesia and intensive care and is at the same time intended to serve as a useful practical guide that will assist in improving outcomes. The topics covered are wide ranging and include, for example, use of the prone position in ARDS, the role of therapeutic hypothermia in the critically ill, the value of immunoglobulins in the treatment of severe sepsis, drug management of septic shock, new strategies for prevention of ventilator-associated pneumonia, non-invasive ventilation outside of the ICU, management of postoperative bleeding and prognostic factors in cardiac arrest. Written by recognized experts in the field, the book will offer a comprehensive and easy to understand update for specialists and students of anesthesia and intensive care.
Oxford Textbook of Critical Care
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summ...
Non-Invasive Respiratory Support, Third edition
The field of non-invasive ventilation continues to expand rapidly since publication of the second edition of Non-Invasive Respiratory Support, new controversies have arisen and numerous practical guidelines have been issued. This expanded third edition with new international contributors has been fully revised and updated. It builds on the success
Cystic Fibrosis
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