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Diabetes mellitus, one of the most prevalent complications during pregnancy, can cause a range of problems for women and their developing babies. The number of types of diabetes during pregnancy has dramatically increased worldwide in recent years. Obesity is a very common risk factor for the development of GDM and type 2 diabetes. To prevent birth defects and other health problems, optimal healthcare before and during pregnancy is mandatory. To reach this goal, a multidisciplinary approach is of major importance. This book presents the latest knowledge on the physiopathology, diagnosis, autoimmunity, genetics, omics, and management and treatment of diabetic pregnancy. Renowned healthcare professionals and academic experts provide insights into the complexity of diabetic pregnancy, its treatment, and pregnancy complications. This is a comprehensive overview of the clinical characteristics of pregnancy-related type 1 and 2 diabetes as well as of gestational diabetes. It is a must-read for everyone involved in the monitoring of diabetes during pregnancy.
There has been a rapid expansion of knowledge in the field of paediatric calcium and bone disorders over the past twenty years. Advances have been made in the underlying genetic basis for many conditions in conjunction with progress in bone density and geometry imaging and the development of new treatment options. The 2nd revised edition of ‘Calcium and Bone Disorders in Children and Adolescents’ presents up-to-date information on many aspects included in the 1st edition such as the physiology, pathology, diagnosis and management of numerous conditions including a chapter of case histories illustrating clinical aspects. New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. Providing a comprehensive update, this book is a useful clinical resource for paediatricians and specialists in endocrinology, metabolic bone disease, nephrology, rheumatology, radiology, orthopaedics and clinical genetics who may be faced with a child with a calcium and/or bone disorder.
This reprint of 'Cytogenetic and Genome Research' contains contributions discussing the subject in-depth. 'Cytogenetic and Genome Research' is a well-respected, international peer-reviewed journal in genetics.
This book is a collection of 22 per-reviewed scientific papers on the synthesis and characterization of polyurethanes with special chemical and physical properties. In our "plastic age", polyurethanes are one of the most versatile polymers with broad and excellent mechanical and chemical properties. These polyurethanes can be found in many areas of our every day`s life ranging from insulators through hard and soft foams to various biomedical devices. The huge number of possible variations in the types of reactants allows the scientists to design and tailor the properties of polyurethanes to specific needs. The fascinating chemistry and materials science of polyurethanes have attracted intere...
Cystic fibrosis used to be thought of as a respiratory and digestive disease, with a uniformly and rapidly fatal outcome. The spectrum of the disease has broadened into the mild atypical case, presenting in middle age, with the potential for complications in virtually every system of the body. In the past few years there has been an explosion of knowledge of the basic science of the defect. The editors have therefore invited the leading scientists and clinicians in the field of cystic fibrosis to describe the recent advances in this disease. Although there are many �Recent Advances� texts, previous books have been selective in their choice of topics. This book is the first to cover the e...
Chlamydiae are obligate intracellular bacteria that cause one of the most common sexually transmitted infectious diseases in the world. The infection disproportionately impacts women and the highest prevalence of infection is found in adolescents. Most chlamydial infections are asymptomatic. Untreated infections are sources of further spread of infection and can lead to serious consequences including pelvic inflammatory disease, infertility and chronic pelvic pain. Chlamydial infections also increase a person’s susceptibility to HIV and other STDs.Featuring contributions by internationally recognized experts in epidemiology, infectious disease research and chlamydial biology, this book pro...
Erosive tooth wear is a multifactorial condition of growing concern to the clinician and the subject of extensive research. Since the publication of the first edition of the book with the title Dental Erosion, new knowledge for a better understanding of this important subject has been gathered. The new and more detailed insights resulted in this second, extended publication. It presents a broad spectrum of views, from the molecular level to behavioural aspects, as well as trends in society. In particular, the issues concerning chemical and biological factors as well as dental erosion in children are covered more extensively in this second edition. The first chapters include topics such as the definition, diagnosis, interaction, epidemiology and histopathology of tooth wear. Further, the aetiology of dental erosion, including nutritional and patient-related factors, and dental erosion in children are discussed. This book is a valuable and indispensable guide to better oral health and is highly recommended to faculty members, researchers, dental students, practitioners and other dental professionals.
In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating f...
A multitude of new developments, not only in the rapidly advancing field of molecular genetics and steroid metabolism but in all traditional areas of pediatric endocrinology, have influenced the diagnostic approach in children and adolescents with endocrine disorders, thus warranting this 4th, revised and extended edition of 'Diagnostics of Endocrine Function in Children and Adolescents'. Several chapters have been revised completely and all have been thoroughly updated. In addition, new chapters dealing with the muscle-bone unit and bone metabolism have also been incorporated. The original format of the chapters, which are a combination of in-depth discussion of the diagnostic process, prac...
Overweight and obesity have quite recently become a major problem affecting many countries worldwide. This publication gives a comprehensive overview on the current knowledge of the pathophysiological mechanisms in the regulation of hunger and satiety. An insight into the important facets of symptomatology, epidemiology, etiology and the treatment of obesity and BED in adults is given and in one chapter the pros and cons of designating BED as a disorder are discussed. The interaction of biological, sociological and psychological factors in the development and maintaining of obesity and BED as well as treatment options both from the medical and from the psychological viewpoints are outlined. An exclusive overview on the prevalence rates, symptomatology, course and treatment approaches of obesity and BED in childhood is presented. General physicians as well as psychologists, pediatricians and psychiatrists interested in obesity and BED in children and adults will find in this book an excellent overview of the latest research.