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Steroid hormones have important roles in human physiology, but they are also implicated in the development of hormone-dependent cancers and various non-maligant diseases. Furthermore, changes in the concentrations of steroid hormones have important effects on the homeostasis of pre- and post-menopausal women, as well as of men in andropause. The associations of steroid hormones with pathophysiological processes and the altered mechanisms of their actions in disease are still not completely understood. It has been known for more than thirty years that in addition to their endocrine activity, steroid hormones act in an intracrine manner. In target organs, active androgens and estrogens can be ...
When Paul meets Marie outside the headmaster’s office it’s hardly love at first sight. More like “what you playing at you frigging psycho?” And when the two sixteen-year-olds find out Marie is pregnant, things get a little dicey. But hindsight is a wonderful thing, and as a grown up Paul waits to meet his children for the first time it’s time for some serious thinking. “I drink too much, my toilet looks like a bomb site and I eat crisps for breakfast. I’m not fit to be someone’s father”.
"Despite their bickering stage double act on the Leeds pub circuit, Mike and his seventeen year old daughter Becky are close. She pretends not to laugh at his jokes, he pretends not to encourage her singing career. Then Becky's behaviour starts to become very unusual. The Lemon Princess is the story of a very British family and a very British political cover-up."--BOOK JACKET.
Two London girls visit Jamaica for a holiday and for romance. Babs wants to know if her romance with Passion, a guy from last year, is for keeps. Anisha is there for different reasons, but she isn't saying what they are – yet. Off Camera was performed at the West Yorkshire Playhouse, 27 June - 12 July, 2003, and was winner of the Alfred Fagon Prize.
Rasha is 30 and it's all gone wrong. His alcoholic father has taken the toilet door, he's got a 16-year-old schoolgirl in his bed and his best friend is the lunatic living downstairs. To top it all, his country has gone to pot. When an old school friend turns up, it's the start of an evening where the sparks and ketchup fly.
A ruthless illegal immigrant rises to the top, exposing the underbelly of the labor market.
A dark, gritty play from a Leeds born writer.