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Oral Infections and General Health
This book provides a wide-ranging update on the associations between oral infections and general health. Detailed consideration is given to the underlying mechanisms or pathways linking oral infections to general health, including metastatic spread of infection from the oral cavity as a result of transient bacteremia, metastatic injury from the effects of circulating oral microbial toxins, and metastatic inflammation caused by immunological dysfunction induced by oral microorganisms. The book also reviews the complex structure and development of oral biofilms in health and disease, and the molecular tools that are currently available for their analysis. The advantages and limitations of such techniques, as well as their impact on the future of diagnostics, prevention and patient management, are discussed.
Dental Caries
Authoritative and comprehensive resource on the disease process and clinical management of dental caries. Dental Caries: The Disease and Its Clinical Management, 4th Edition maintains the same focus on high-level coverage of the disease etiology and process, clinical assessment and prognosis and wider public health issues connected with dental caries management, including an enhanced focus on caries control. Fully updated throughout, the chapters that discuss theory emphasize how the knowledge can be applied in both the clinic and in the public health domain to improve oral health. The new edition also includes up-to-date and validated diagnostic and management options for caries whilst ensu...
Dry Mouth, The Malevolent Symptom
Xerostomia, more commonly called dry mouth, affects an estimated 20 percent of adults worldwide and can severely diminish one’s quality of life. Dry Mouth, the Malevolent Symptom: A Clinical Guide relies on evidence-based research to provide an introductory primer on oral dryness and the modalities available to treat it. The book describes the varied etiology of the disease, but emphasizes clinical protocols and step-by-step procedures for diagnosis and treatment planning. Dry Mouth is a user-friendly manual guiding clinicians through identifying and managing this common condition. Causes including radiotherapy, chemotherapy, systemic diseases, polypharmacy, and the natural progression of aging are discussed in conjunction with the clinical symptoms and signs associated with each one. Multiple avenues for treatment are presented, highlighting salivary stimulation and supplementation techniques, pharmacologic aids, and critically required oral therapy. Although intended primarily for the professionals that treat those affected by xerostomia, Dry Mouth may also be of interest to sufferers of this condition.
Dry Mouth
This wide-ranging guide to dry mouth, or xerostomia, is intended to meet the needs of dentists by providing information on all clinically relevant aspects. After introductory discussion of salivary secretion and function, the potential causes of dry mouth, including diseases affecting saliva production, drugs and irradiation, are examined. Symptoms and signs such as altered taste, bacterial changes and infection are discussed and impacts on quality of life, described. Diagnostic issues are fully explored, covering the use of clinical scoring scales, difficulties in assessment, detection of early signs and the role of salivary biomarkers. The full range of treatment options and preventive measures is then described, including the use of intensity-modulated radiotherapy to spare salivary function, the value of artificial salivas and the beneficial effects of regular chewing. The book closes by considering future treatment avenues and the potential for salivary gland regeneration.
Clinical Oral Physiology
This textbook provides a comprehensive overview of the part of dentistry that links basic physiologic and pathophysiologic mechanisms to frequently encountered problems in dental practice. It features the contributions of outstanding researchers and clinicians from across the spectrum of fields relevant to dentistry. The easy-to-read and systematic approach of the book makes it appropriate for undergraduate and postgraduate dental students as well as for practicing clinicians who wish to keep abreast of emerging oral physiologic issues and their clinical implications.
Filaggrin
Filaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reaching a prevalence of up to 10%. Filaggrin proteins are crucial for skin homeostasis as their metabolites maintain skin hydration, keep the skin pH low, and provide protection against solar radiation. FLG mutation carriers suffer from dry and scaly skin and have an increased transfer of allergens and chemicals across the epidermis. Moreover, they have 10% higher serum vitamin D levels, potentially affecting the propensity to develop other diseases. FLG loss-of-function mutations represent the strongest risk factor hitherto discovered for atopic dermatitis and are major predisposing factors for related asthma and hay fever. This textbook provides comprehensive and detailed coverage of the effects of FLG mutations in health and disease (cutaneous and non-cutaneous) and also discusses the basic science, epidemiology, management, and future research areas.
100 Million Years of Food
“A fascinating journey [with] a few salient conclusions: primarily that we’d all be a lot better off if we ate like our great-great-great grandparents.” —National Post There are few areas of modern life that are as burdened by information and advice, often contradictory, as our diet and health. In 100 Million Years of Food, biological anthropologist Stephen Le explains how cuisines of different cultures are a result of centuries of evolution, finely tuned to our biology and surroundings. Travelling around the world to places as far-flung as Vietnam, Kenya, India, and the US, Stephen Le introduces us to people who are growing, cooking, and eating food using both traditional and modern...
Orofacial Pain
When it comes to mechanisms, diagnosis, and management of acute and chronic orofacial pain, no book is more comprehensive than Orofacial Pain. With 54 leading pain specialists documenting the latest research advances and treatments, this book is the new standard resource for understanding, assessing, and managing all aspects of orofacial pain. Orofacial Pain’s 24 chapters address the epidemiologic, socioeconomic, and psychological aspects of orofacial pain conditions as well as the mechanisms underlying orofacial pain revealed in recent studies in humans and animals. Most other books on this topic focus on just one or two aspects of orofacial pain—and nearly all with only dental students or clinicians in mind. Orofacial Pain provides the most up-to-date, complete, and integrated coverage of advances in research and new evidence. It is must reading not only for dental clinicians but also for pain scientists and specialists, neurologists, and other clinicians.
