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Impact of Dietary Vitamin D on Immunoregulation and Disease Pathology in Lupus-prone NZB/W F1 Mice
Abstract: Vitamin D (VD) deficiency is a highly prevalent worldwide phenomenon and is extensively discussed as a risk factor for the development of systemic lupus erythematosus (SLE) and other immune-mediated diseases. In addition, it is now appreciated that VD possesses multiple immunomodulatory effects. This study aims to explore the impact of dietary VD intake on lupus manifestation and pathology in lupus-prone NZB/W F1 mice and identify the underlying immunological mechanisms modulated by VD. Here, we show that low VD intake accelerates lupus progression, reflected in reduced overall survival and an earlier onset of proteinuria, as well higher concentrations of anti-double-stranded DNA a...
The Little Prince
"Get your "A" in gear! They're today's most popular study guides-with everything you need to succeed in school. Written by Harvard students for students, since its inception "SparkNotes(TM) has developed a loyal community of dedicated users and become a major education brand. Consumer demand has been so strong that the guides have expanded to over 150 titles. "SparkNotes'(TM) motto is "Smarter, Better, Faster because: - They feature the most current ideas and themes, written by experts. - They're easier to understand, because the same people who use them have also written them. - The clear writing style and edited content enables students to read through the material quickly, saving valuable time. And with everything covered--context; plot overview; character lists; themes, motifs, and symbols; summary and analysis, key facts; study questions and essay topics; and reviews and resources--you don't have to go anywhere else!
Code of Federal Regulations
Special edition of the Federal Register, containing a codification of documents of general applicability and future effect ... with ancillaries.
Bulletin des lois. Partie supplémentaire
Bulletin des lois, 2e partie. Ordonnances, 1e et 2e section
