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This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating an introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers. A simplified introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers Approaches learning from the vantage point of clinical questions on therapy, diagnosis, prognosis or harm rather than the framework of study designs Provides tables and boxed case studies throughout highlighting key topics, or difficult issues, in an easy to read manner Emphasizes applicability of EBM, encouraging readers to dissect the evidence and how results can be applied to individual patients with different circumstances, varying values and preferences New to the Second Edition are chapters on health screening, clinical practice guidelines, and major updates incorporating recommended trial criteria
Volume Two of this retrospective bibliography is both a continuation and an expansion of Volume One (1984). It contains references to Canadian medical-historical literature published between 1984 and 1998, and also includes much additional material published prior to 1984. Finally, it substantially enlarges the content of French-language material. Every effort has been made to be as inclusive as possible of articles, theses, book chapters and books, both in English and in French, relating to the history of medicine. No single electronic source can replace this bibliography. The contents are divided into three sections. The first is a listing of material expressly biographical. Section two lists material under a wide variety of subject headings related to medicine, and the third is a complete listing of the authors who have contributed these articles. Simply organized and easy to use, this bibliography will be of value to historians, archivists, librarians, and anyone interested in the history of medicine.
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Correlates of Protection (CoP) are biological parameters present in vaccinated or naturally infected individuals that predict levels of protection against an infectious disease. CoP facilitate vaccine licensing since they enable: a) the selection of antigen composition of a vaccine; b) the assessment of vaccine efficacy in clinical trials without exposure of participants to natural infection; and c) bridging between first- and second-generation vaccines.
Volume 51