Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Brain Insulin Resistance in Neurodevelopmental and Neurodegenerative Disorders: Mind the Gap!
The failure of insulin signaling – a condition known as insulin resistance – is a key pathological feature of both type 2 diabetes (T2DM, systemic insulin resistance) and Alzheimer’s disease and related dementias (ADRDs, brain insulin resistance) and greatly contribute to their development. Considerable overlap has been identified in the risk factors, comorbidities and putative pathophysiological mechanisms of ADRDs and T2DM, thus proposing AD as type 3 diabetes.
New Prognostic and Predictive Markers in Cancer Progression
Biomarkers are of critical medical importance for oncologists, allowing them to predict and detect disease and to determine the best course of action for cancer patient care. Prognostic markers are used to evaluate a patient’s outcome and cancer recurrence probability after initial interventions such as surgery or drug treatments and, hence, to select follow-up and further treatment strategies. On the other hand, predictive markers are increasingly being used to evaluate the probability of benefit from clinical intervention(s), driving personalized medicine. Evolving technologies and the increasing availability of “multiomics” data are leading to the selection of numerous potential bio...
The Hospitaller Grand Priory of Messina in the Seventeenth Century
This book details the origin of the Grand Hospitaller Priory of Messina. It discusses a breadth of themes, such as the historiography, the Hospitaller’s European commandery and Sicilian patrimony, its management and organization in the seventeenth century, its religious practices, and the prioral mansion in Messina. The final chapter includes a detailed account of the 1674 Messina insurrection against the Spanish overlords. This event plunged the priory into political chaos, fracturing it and pitting members against each other. It also shattered neutrality issues embedded in the statutes of the religion and ignoring the precepts emanating from the Convent on Malta. The Hospitaller Grand Priory of Messina in the Seventeenth Century will appeal to students and scholars alike interested in the Crusading Orders, the history of the Knights Hospitaller, and the history of Malta.
Athene
None
Nuclear Receptors
Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases. This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins. World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working ...
Catalogue
None
