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Artificial Cells
The first part of the monograph is a consideration of the general characteristics of artificial cells and specific theoretical examples of artificial cell systems. This is followed by examples of typical preparative procedures which have been updated. The biophysical properties of artificial cells are characterized. They are then used in experiments designed to test some of the theoretical examples.
Artificial Cells, Cell Engineering and Therapy
Artificial cells, cell engineering and therapy are emerging technologies which will make a significant impact on the future of medicine and healthcare. However, research within the field is vast. This unique book provides a comprehensive study of the most recent advances in the field and its practical applications.The first part of the book offers the reader an introduction to the basics of artificial cell technology with chapters on its origins, design, current status within medicine and future prospects. Part two covers apoptosis, the use of bone marrow stromal cells in myocardial regeneration together with signalling and tissue engineering. Part three discusses artificial cells for therap...
Artificial Cells
50th anniversary of artificial cells -- Basic principles -- Oxygen carriers based on nanobiotechnology -- A nanobiotechnologic therapeutic that transports oxygen and remove oxygen radicals: for stroke, hemorrhagic shock and related conditions -- Nanotechnology-based artificial red blood cells (RBC's) -- Use of enzyme artificial cells for genetic enzyme defects that increase systemic substrates to toxic levels -- Enzyme artificial cells in substrate-dependent tumors and activation of prodrug -- Artificial cells for cell encapsulation -- Artificial cells containing hepatocytes and/or stem cells in regenerative medicine -- Hemoperfusion in poisoning, kidney failure, liver failure, and immunology -- Perspectives on the future of artificial cells as suggested by past research.
Artificial Cells
This is the first book that provides a comprehensive review of the entire area of artificial cells. The author, a pioneer of the field, invented the first artificial cells some 50 years ago and has continued to carry out active research in this field. Since then, there have been explosive research activities around the world on artificial cells, especially in fields related to biotechnology, nanomedicine, cell therapy, blood substitutes, drug delivery and others. However, instead of the term ?artificial cells,? many authors use other terminologies such as blood substitutes, bioencapsulation, liposomes, nanoparticles and so on. Furthermore, papers in this highly interdisciplinary area are pub...
Synthetic Biology
Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystem...
Selected Topics In Nanomedicine
Nanomedicine consists of the use of nanotechnology and nanobiotechnology in medicine. There have been extensive developments in the area of nanomedicine. The scope of this book is first to discuss the origin of nanomedicine. Following this, instead of a general overview of the whole area, 24 chapters on selected topics of important areas are described in detail. Authors are selected from around the world to give a representative and international view of the activities in the area of nanomedicine.
Microcapsules and Nanoparticles in Medicine and Pharmacy
First published in 1992: This book provides a comprehensive look at the design and production of microcapsules, microspheres, and nanoparticles. It discusses the diverse aspects and skills that must be mastered to prepare and test products that will work correctly and be clinically acceptable for human or animal use.
Cell Encapsulation Technology and Therapeutics
The concept of using encapsulation for the immunoprotection of transplanted cells was introduced for the first time in the 1960s. "[Microencapsulated cells] might be protected from destruction and from partici pation in immunological processes, while the enclosing membrane would be permeable to small molecules of specific cellular product which could then enter the general extracellular compartment of the recipient. For instance, encapsulated endocrine cells might survive and maintain an effective supply of hormone." (Chang, Ph. D. Thesis, McGill University, 1965; Chang et aI., Can J Physiol PharmacoI44:115-128, 1966). We asked Connaught Laboratories, Ltd., in Toronto to put this concept int...
