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Transposable Elements and Genome Evolution
Since their discovery by Barbara McClintock in the mid-20th century, the importance of transposable elements in shaping the architecture, function and evolution of genomes has gradually been unveiled. These DNA sequences populate nearly all genomes and are viewed as genomic parasites. They are mobile, capable of proliferating within genomes and also commonly travel between species. These elements are mutagenic and are responsible for several human genetic disorders, but they also constitute a major source of genetic diversity. Some insertions have beneficial effects for the host and are selected for, giving rise to significant evolutionary innovations. Their dynamics within genomes are intricate, as are their interactions with other genome components. To limit their proliferation, the genome has evolved sophisticated defense mechanisms. While researchers commonly use these elements as genetic tools, their identification in newly sequenced genomes remains a challenge due not only to their extensive diversity, but also their large copy numbers.
Evolution and Impact of Transposable Elements
During the last 50 years, the perception oftransposable elements (TEs) has changed considerably from selfish DNA to sequences that may contribute significantly to genome function and evolution. The recent increased interest in TEs is based on the realization that they are a major genetic component (at least 10--20%) of all organisms and a major contributor to the mutation process. It is currently estimated that 70--80% of spontaneous mutations are the result of TE-mediated insertions, deletions, or chromosomal rearrangements. Thus, it seems at least plausible that TEs may playa significant role in the adaptation and evolution of natural populations and species. The ubiquity of TEs suggests t...
Self-Spreading Biotechnology and International Law
Wer haftet, wenn sich selbst ausbreitende Gentechnik grenzüberschreitende Schäden verursacht? Mit Gene Drives und ähnlichen Verfahren wird es bald möglich sein, das Erbgut wild lebender Arten, Keime und Nutzpflanzen direkt in der Umwelt zu verändern. Dies könnte helfen, drängende Probleme in der öffentlichen Gesundheit, im Naturschutz und in der Ernährungssicherheit zu lösen. Allerdings bergen diese Verfahren auch das Risiko einer unkontrollierten Ausbreitung über Staatsgrenzen hinweg. Anhand einer grundlegenden Untersuchung der einschlägigen Verträge und des Völkergewohnheitsrechts zu Prävention und Haftung für grenzüberschreitende Schäden wird aufgezeigt, dass das derzeit geltende Völkerrecht dieser Herausforderung noch nicht gewachsen ist.
Transposable Elements and Genome Evolution
Since their discovery by Barbara McClintock in the mid-20th century, the importance of transposable elements in shaping the architecture, function and evolution of genomes has gradually been unveiled. These DNA sequences populate nearly all genomes and are viewed as genomic parasites. They are mobile, capable of proliferating within genomes and also commonly travel between species. These elements are mutagenic and are responsible for several human genetic disorders, but they also constitute a major source of genetic diversity. Some insertions have beneficial effects for the host and are selected for, giving rise to significant evolutionary innovations. Their dynamics within genomes are intricate, as are their interactions with other genome components. To limit their proliferation, the genome has evolved sophisticated defense mechanisms. While researchers commonly use these elements as genetic tools, their identification in newly sequenced genomes remains a challenge due not only to their extensive diversity, but also their large copy numbers.
علم الجراثيم الأساسي
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Genetics Abstracts
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European Traditions in Didactics of Mathematics
This open access book discusses several didactic traditions in mathematics education in countries across Europe, including France, the Netherlands, Italy, Germany, the Czech and Slovakian Republics, and the Scandinavian states. It shows that while they all share common features both in the practice of learning and teaching at school and in research and development, they each have special features due to specific historical and cultural developments. The book also presents interesting historical facts about these didactic traditions, the theories and examples developed in these countries.
Fusarium
Diseases caused by Fusarium and their control; The fungus Fusarium: ecology; The fungus Fusarium: genetics and cytology; The fungus Fusarium: Physiology and histopathology; The fungus Fusarium: Taxonomy.
Oogenesis
Oogenesis - the process by which female germ cells develop into mature eggs, or ova - is a complex process involving many important elements of developmental and cellular biology: from cell-cell interactions, complex signalling cascades, specialized cell cycles and cytoskeleton organization. Oocytes from various species (including clam, starfish, xenopus and mouse) are excellent model systems to study the biochemistry of cell division with important implications for basic and clinical research. This book describes the entire process of oogenesis in chronological order with contributions from leading international researchers and chapters covering medical and ethical considerations in oogenic...
Bryophyte Ecology and Climate Change
Bryophytes, especially mosses, represent a largely untapped resource for monitoring and indicating effects of climate change on the living environment. They are tied very closely to the external environment and have been likened to 'canaries in the coal mine'. Bryophyte Ecology and Climate Change is the first book to bring together a diverse array of research in bryophyte ecology, including physiology, desiccation tolerance, photosynthesis, temperature and UV responses, under the umbrella of climate change. It covers a great variety of ecosystems in which bryophytes are important, including aquatic, desert, tropical, boreal, alpine, Antarctic, and Sphagnum-dominated wetlands, and considers the effects of climate change on the distribution of common and rare species as well as the computer modeling of future changes. This book should be of particular value to individuals, libraries, and research institutions interested in global climate change.
