Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Emerging immune functions of non-hematopoietic stromal cells
The development and function of the immune system is dependent on interactions between haematopoietic cells and non-hematopoietic stromal cells. The non-hematopoietic stromal cells create the microenvironment in which the immune system operates, providing an architectural landscape for hematopoietic cell-cell interactions and molecular cues governing haematopoietic cell positioning, growth and survival. Not surprisingly, therefore, aberrant stromal cell function has recently been shown to play a key role in the development of disease pathologies associated with immune dysfunction. For example, remodelling of lymphoid tissue stroma and the development of ectopic tertiary lymphoid tissues are ...
Superplasticity of Alloys, Intermetallides and Ceramics
Superplasticity is shown to be a universal phenomenon in materials ranging from metals and intermetallics to ceramics. Superplastic deformation facilitates the production of materials with specifically chosen properties. This is illustrated using the examples of Mg-, Al-, and Ti-based commercial alloys, steels, and superalloys. Some of the strenghts of this book are: the broad range of materials studied, the reduction of scientific results to a form suitable for the practitioner, a profound physical analysis of the phenomenon, a new approach to superplastic treatment as a kind of strain-heat treatment, the presentation of new data on superplastic flow and on production techniques of micro- and submicrocrystalline structures.
Accelerated Path to Cures
Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical trials and post-approval monitoring, as alternative models of drug development. As a case of successful integration of computational modeling and drug development, we discuss the development of oral small molecule therapeutics for inflammatory bowel disease, from the application of docking studies to screening new chemical entities to the development of next-generation in silico human clinical trials from large-scale clinical data. Additionally, this book illustrates how modeling techniques, machine learning, and informatics can be utilized effectively at each stage of drug development to advance the progress towards predictive, preventive, personalized, precision medicine, and thus provide a successful framework for Path to Cures.
Coffee and Coffeehouses
Drawing on the accounts of early European travelers, original Arabic sources on jurisprudence and etiquette, and treatises on coffee from the period, the author recounts the colorful early history of the spread of coffee and the influence of coffeehouses in the medieval Near East. Detailed descriptions of the design, atmosphere, management, and patrons of early coffeehouses make fascinating reading for anyone interested in the history of coffee and the unique institution of the coffeehouse in urban Muslim society
Handbook of Plant-Based Food and Drinks Design
Handbook of Plant-Based Food and Drinks Design discusses conventional and emerging technologies for plant-based ingredient improvement (yield, nutritional composition and functional properties) while considering food safety, sustainability, and social impact to explore current and potential markets through research and innovation. Divided in 7 sections, the book covers Plant sources for functional ingredients, Processing plant-based sources, Plant-based food design to replace/mimic animal food, Innovation in plant-based food, The promise of parity, Safety and regulations of plant-based foods, Social, environmental, and economic impact, and more. Written by a team of experts in the field, this book can be a good support for researchers and scientists working with plant-based food, drinks, and market trends. - Brings a critical overview about the health-beneficial compounds of plant-based sources - Offers guidelines on how to formulate plant-based food or a food alternative - Discusses the transition towards more plant-based diets on nutrition, economy climate change, health, and sustainability
Ion Channels
Ion channels are intimately involved in the everyday physiological functions that enable us to live a full and varied life. When disease strikes, malfunction of ion channels or their dependent is often involved, either as the cause or the effect of the illness. Thus, billions of dollars have been, and still are being, invested in research to understand the physiological and pathophysiological functions of ion channels in an attempt to develop novel therapeutic treatments for a wide range of diseases. This book provides a comprehensive overview of ion channel structure and function. It comprises two major parts. Part one is an introductory overview of the ion channel superfamily and the gener...
A Historical-Etymological Dictionary of Pre-Russian Habitation Names of the Crimea
This dictionary, the first of its kind in Turkological studies, will prove to be an invaluable research tool for those studying the Crimea, Ukraine, as well as Eurasian Nomadism. It is the result of year-long painstaking research into the etymology of Crimean pre-Russian habitation names, providing insight into the Turkic, Greek, Caucasian place-names in a comparative context, as well as the histories of these cities, towns and villages themselves. The dictionary contains approximately 1,500 entries, preceded by an introduction with notes on the history of the Crimea and the structure of habitation names. For the reader’s convenience, many entries are classified in indices which follow the main part of the book. Additionally, three detailed primary source maps, separately indexed, are appended to the dictionary, as well as a map showing the administration network of the Crimea at the end of the Crimean Tatar Khanate.
