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From Caracas to Stockholm
The memoir of immunologist and 1980 Nobel prize winner Benacerraf. Born in 1920 to a family of Jewish textile importers in Caracas, Venezuela, he moved to Paris at the age of five. He discusses his years studying at the Lycee Janson and the period of the Nazi invasion of France which led the family to flee back to the Americas where he found himself studying medicine in the United States. His years at Harvard, NYU, and the National Institute of Health are examined, as is his time as the chief executive officer of the Dana-Farber Cancer Institute. Annotation copyrighted by Book News, Inc., Portland, OR
Advances in Cancer Research
Advances in Cancer Research
Truth, Objects, Infinity
This volume features essays about and by Paul Benacerraf, whose ideas have circulated in the philosophical community since the early nineteen sixties, shaping key areas in the philosophy of mathematics, the philosophy of language, the philosophy of logic, and epistemology. The book started as a workshop held in Paris at the Collège de France in May 2012 with the participation of Paul Benacerraf. The introduction addresses the methodological point of the legitimate use of so-called “Princess Margaret Premises” in drawing philosophical conclusions from Gödel’s first incompleteness theorem. The book is then divided into three sections. The first is devoted to an assessment of the improv...
Immunopharmacology
Immunopharmacology is the 11th volume of the proceedings of the Third International Pharmacological Meeting held at Sao Paulo, Brazil on July 26, 1966. The volume covers papers that deal with immunoglobulins responsible for hypersensitivity reactions and with the mechanisms of these reactions; pharmacological mediators of immediate and delayed hypersensitivity; Arthus reactions; and soluble factors released by the action of antigen on sensitized lymphocytes. The book concludes with a single paper on the subject of penicillin allergy. Immunologists and pharmacologists will find the volume invaluable.
Clinical Cellular Immunology
The initial impetus to create a work combining aspects of cel lular immunology with their clinical applications grew from the ed itors' discussions of the area's needs with many of the leaders in the field over a period of time. From the nucleus of ideas that emerged, we have here attempted to create a unified and inte grated coverage of the rapidly growing field of cellular immunology research and to trace out-from what seems at times a genuine plethora of important new findings-the many and often impor tant clinical implications. Because of this approach, the chapters of Clinical Cellular Im munology attempt to be more than critical reviews of research and clinical data, going beyond analy...
Immunology for the Practicing Physician
The field of immunology has grown extensively during the past decadeo The basic concepts and importance of these findings may have clinical application in the management, detection, and ex planation of human diseases. Therefore, when a topic was to be chosen for the dedication of the new Metropol itan Medical Center, in Minneapolis, Minnesota, immunology, and its relation to medi cine, was selected. In fact, "applied immunology has had great impact on all aspects of medical practice. This impact has taken several forms: modern immunology has defined areaS of new medical practice (in the immunodeficiency disease, for example); has lent strength to the development of other areaS (such as trans...
T and B Lymphocytes: Recognition and Function
T and B Lymphocytes: Recognition and Function is the 16th volume of the 1979 ICN-UCLA Symposia on Molecular and Cellular Biology. This book is organized into seven sections, encompassing 74 chapters that summarize molecular level progress in the field of immunobiology. It emphasizes cell membrane, techniques developed for its analysis, and varied products of the major histocompatibility complex, as well as other receptors on cells of the immune system. The book starts by describing two approaches for molecular association evaluation. First is the use of artificial membranes or lipid vesicles for the incorporation of antigens for recognition by T-lymphocytes both at the afferent and efferent ...
The Immune System
The Immune System: Genes Receptors, Signals provides information pertinent to the complexity of immune mechanisms. This book describes the immune response genes and products, which point to another multigene system controlling immune responsiveness. Organized into 37 chapters, this book begins with an overview of the details of antibody structure that continue to be of importance to an understanding of the regulation of the immune reactions. This text then examines the evidence that individual antibody species are capable of binding many structurally dissimilar haptens. Other chapters consider the conceptual framework generally accepted by immunologists, which states that antibodies are specific for the antigen used to elicit the immune response. This book discusses as well the mechanism underlying the biosynthesis of antibody binding sites, which is unprecedented in its adaptability. The final chapter deals with the genetic controls of specific immune responses. This book is a valuable resource for immunologists and research workers.
Macrophage Regulation of Immunity
Macrophage Regulation of Immunity contains the proceedings of a conference held in Augusta, Michigan, on March 12-14, 1979. The papers examine the role of macrophages in the regulation of cellular immune reactions. They highlight the interaction between macrophages and T cells, along with immune response gene control and macrophage secretion of a number of lymphostimulatory molecules. Organized into six sections encompassing 35 chapters, this volume begins with an overview of antigen handling and presentation, immune response gene control, antigen-presenting cells, and factors affecting lymphocyte-macrophage interactions. It then discusses genetic control of T cell-macrophage interaction in helper cell induction in vitro; mechanisms underlying the interaction of guinea pig T lymphocytes with antigen-pulsed macrophages; and secretion of arachidonic acid oxygenation products by mononuclear phagocytes and their possible role as modulators of lymphocyte function. The book also covers regulation of intracellular killing by extracellular stimulation of the monocyte membrane, and adjuvant activation of macrophage functions. Students and scientists will find this book extremely helpful.
The Reticuloendothelial System and Atherosclerosis
The circulatory system is usually considered to be composed of tubes of various diameters, characterized by collateral and terminal branches. There is also a tendency to treat blood vessels merely as conducting tubes in which the various structures of the wall act as mechanical pumps wlrich modify their diameter. This is, of course, not so. In fact, we know that blood vessels, and in particular arteries, are organs with personalities of their own and a particular susceptibility to several diseases. In addition, blood vessels differ in structure, according to their localization, and age at differing rates. The experimental work car ried out so far clearly confirms the data that have come from...
