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Brucellosis, also known as undulant fever, Mediterranean fever, or Malta fever, is an important human disease in many parts of the world. It is a zoonosis and the infection is almost invariably transmitted to people by direct or indirect contact with infected animals or their products. These Guidelines are designed as a concise, yet comprehensive, statement on brucellosis for public health, veterinary and laboratory personnel without access to specialized services. They are also to be a source of accessible and updated information for such others as nurses, midwives and medical assistants who may have to be involved with brucellosis in humans. Emphasis is placed on fundamental measures of environmental and occupational hygiene in the community and in the household as well as on the sequence of actions required to detect and treat patients.
Brucellosis is a major zoonotic disease that may cause a serious illness in humans and animals. Global prevalence of human brucellosis remains significant. More than half a million new brucellosis cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of these cases are reported in developing countries.In humans, brucellosis (undulant fever, Malta fever) is characterized by an acute bacteremic phase followed by a chronic stage that may extend over many years and may involve many tissues. It is a systemic disease, and many organ systems (nervous system, heart, skeletal system, bone marrow, etc.) may become involved following hematogenous disseminat...
A full description of the clinical aspect and pathology of the disease, with a discussion of current treatment. This updated edition includes five new chapters: endocrinal brucellosis, difficulties in diagnosis and management, HIV and brucellosis, bioterrorism and brucellae, and spondylitis with neurobrucellosis. The book presents a complete, up-to-date picture of the disorder and will appeal to clinicians, students, researchers and also to veterinarians.
Fourteen brucellosis experts from seven countries discuss the history, epidemiology, microbiology, immunology, diagnosis, treatment, and control of brucellosis in animals and man. Edited by members of the World Health Organization's Expert Committee on Brucellosis, this text is the first comprehensive treatment of the disease since The Nature of Brucellosis by Wesley W. Spink in 1956. Topics reviewed with current references include infection caused by newer species of Brucella, such as B. canis, newer diagnostic techniques, such as radioimmunoassay and ELISA, and newer treatments, such as rifampin and the quinolones. The pathogenesis and pathophysiology of brucellosis is reviewed in depth, correlating the disease in animals with the illness in humans. This volume is extremely useful for clinicians, researchers, and students in medicine, veterinary science, microbiology, immunology, epidemiology, public health, and international health.
This timely publication updates and standardizes currently used diagnostic procedures for this widespread, economically costly livestock disease. It includes state-of-the-art technology, now in limited use, which will replace the conventional methodology in the near future. The volume covers research done on improved diagnostic techniques, vaccines, taxonomy, epidemiology, pathology, and basic immunology. It is an important literature review for those more established in this field and serves as a guide to researchers or diagnosticians becoming involved with this disease.
rope it was mainly the states of the northern and centrat European areas which succeeded in achieving the extermi nation or at least the regression of brucellosis. (The origi nal plan to present the conditions in Asia and Oceania, in cluding Australia, in maps as weil, and thereby to achieve a comprehensive worldwide review of the known and as certainable distribution of brucellosis, was not, however, practicable. ) Information available from these parts of the world, especially from Asia, is so fragmentary that the great expense required for the compilation of the map did not seem justified. On the other hand it seemed desirable to collate and document these data which had been ac quired as...
Brucellosis presents an overview of the conditions associated with the subject matter. It discusses the disease of protean manifestations affecting all types of tissues and organs in the body. It addresses the different facet of the disease studied in isolation. Brucellosis is a zoonotic disease common around the world. Some of the topics covered in the book are the historical origin of different species of Brucella strain; epidemiological features of brucellosis; occupational hazards of working in the meat processing environment; identification and taxonomy of bacteria carrying the Brucella strain; and methods for the identification of cultures. The pathology and immunology of brucellosis in humans are fully covered. The histopathological aspects of the brucella organisms are discussed in detail. The text describes in depth the cardiovascular complications of the disease. The diagnosis of brucella thrombophlebitis is completely presented. A chapter is devoted to the respiratory and gastrointestinal manifestations of brucella organisms. The book can provide useful information to veterinarians, doctors, chemists, students, and researchers.
Latest diagnostic techniques Appendices with detailed methodologies Investigation of other Brucella species as well as Brucella abortus Eradication programs
Brucellosis is an important zoonotic disease. More than half a million new cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of patients are living in developing countries. Brucellosis is a systemic infection with a broad clinical spectrum, ranging from an asymptomatic disease to a severe and fatal illness. Clinical and laboratory features vary widely. The main presentations are acute febrile illness, localized infection, and chronic infection. Laboratory tools for diagnosis of brucellosis include culture, serology, and polymerase chain reaction (PCR). The goal of brucellosis therapy is to control the illness and prevent complications, relaps...