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Peptide-Liposome Model Systems for Triggered Release
Liposomes are widely used in drug delivery to improve drug efficacy and to reduce side effects. For liposome-encapsulated drugs to become bioavailable and provide a therapeutic effect they must be released, which typically is a slow process that primarily relies on passive diffusion, liposome rupture or endocytotic uptake. Achieving drug concentrations within the therapeutic window can thus be challenging, resulting in poor efficacy and higher risks drug resistance. Finding means to modulate lipid membrane integrity and to trigger rapid and efficient release of liposomal cargo is thus critical to improve current and future liposomal drug delivery systems. The possibilities to tailor lipid co...
Handbook of Photosensory Receptors
This first complete resource on photosensory receptors from bacteria, plants and animals compiles the data on all known classes of photoreceptors, creating a must-have reference for students and researchers for many years to come. Among the editors are the current and a former president of the American Society for Photobiology.
Exploring C2 Capability and Effectiveness in Challenging Situations
Modern societies are affected by various threats and hazards, including natural disasters, cyber-attacks, extreme weather events and inter-state conflicts. Managing these challenging situations requires immediate actions, suspension of ordinary procedures, decision making under uncertainty and coordinated action. In other words, challenging situations put high demands on the command and control (C2) capability. To strengthen the capability of C2, it is vital to identify the prerequisites for effective coordination and direction within the domain of interest. This thesis explores C2 capability and effectiveness in three domains: interorganizational crisis management, military command and cont...
Assessing Command and Control Effectiveness
Assessing Command and Control Effectiveness: Dealing with a Changing World offers a description of the current state of Command and Control (C2) research in imperfect settings, showing how a research process should assess, analyse and communicate results to the development cycle of methods, work, manning and C2-technology. Special attention is given to the development of C2 research methods to meet the current and coming needs. The authors also look forward towards a future where effective assessment of C2 abilities are even more crucial, for instance in agile organisations.
The Art of Record Production
The playback of recordings is the primary means of experiencing music in contemporary society, and in recent years 'classical' musicologists and popular music theorists have begun to examine the ways in which the production of recordings affects not just the sound of the final product but also musical aesthetics more generally. Record production can, indeed, be treated as part of the creative process of composition. At the same time, training in the use of these forms of technology has moved from an apprentice-based system into university education. Musical education and music research are thus intersecting to produce a new academic field: the history and analysis of the production of record...
The Art of Record Production
The playback of recordings is the primary means of experiencing music in contemporary society, and in recent years 'classical' musicologists and popular music theorists have begun to examine the ways in which the production of recordings affects not just the sound of the final product but also musical aesthetics more generally. Record production can, indeed, be treated as part of the creative process of composition. At the same time, training in the use of these forms of technology has moved from an apprentice-based system into university education. Musical education and music research are thus intersecting to produce a new academic field: the history and analysis of the production of record...
cis-trans Isomerization in Biochemistry
Collating the knowledge from over 20,000 publications in chemistry, biology and nanotechnology, this handbook is the first to comprehensively present the state of the art in one ready reference. A team of international authors connects the various disciplines involved, covering cis-trans isomerization of double bonds and pseudo-double bonds, as well as other cis-trans isomerizations. For biochemists, organic chemists, physicochemists, photochemists, polymer and medicinal chemists.
Cyber Situational Awareness
Motivation for the Book This book seeks to establish the state of the art in the cyber situational awareness area and to set the course for future research. A multidisciplinary group of leading researchers from cyber security, cognitive science, and decision science areas elab orate on the fundamental challenges facing the research community and identify promising solution paths. Today, when a security incident occurs, the top three questions security admin istrators would ask are in essence: What has happened? Why did it happen? What should I do? Answers to the ?rst two questions form the core of Cyber Situational Awareness. Whether the last question can be satisfactorily answered is greatl...
An Introduction To Systems Science
This is the first book that renders a thorough discussion of systems science. It draws on material from an extensive collection of external sources, including several other books and a special library collection complete with videotape empirical evidence of applicability of the theory to a wide variety of circumstances. This is essential because systems science must be responsive to diverse human situations of the widest difficulty, and it must fill the void that the specific sciences cannot fill, because these sciences are insensitive to the necessities of reconciling disparate views of multiple observers, and incorporating local conditions in hypotheses that precede inductive explorations.
NanoBioMedicine
This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.
