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Carbon Tetrachloride
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Carbon Tetrachloride
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Current Concepts of Acute Carbon Tetrachloride Hepatotoxicity
A literature survey of hydrocarbon-induced, experimental, acute hepatotoxicity was made. It was concluded that carbon tetrachloride, and probably other hydrocarbons, directly interfere with the selective permeability of the liver cell wall and membranous endoplasmic reticulum for electrolytes, water, and certain hydrophilic proteins. Concomitantly the toxin stimulates the sympathetic nervous system and the release of its hormones. These reduce hepatic blood flow, by vasoconstriction, thereby inducing centrilobular hypoxia, degeneration, and necrosis. These also cause massive mobilization of fats from the peripheral depots. These fats accumulate in the liver where their secretion, as triglycerides, is blocked by unknown mechanisms. (Author).
Industrial Solvents Handbook, Revised And Expanded
Keeping pace with current trends in solvent production, this volume builds upon its previous edition with broader coverage of safe handling practices, health effects, physical properties, and chemical synthesis routes to some of the most important organic solvents used in the chemical and allied process industries. This handy reference features a glossary of solvent terminology and an easy-to-reference index of synonyms for chemicals and solvents. The Second Edition features new and updated chapters on the major classes of organic solvents, descriptions for general use, and the chemical formulation, thermodynamic properties, health and toxicity, and combustible characteristics of solvents.
Environmental Medicine
People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.
Hazardous Laboratory Chemicals Disposal Guide, Third Edition
A perennial bestseller, Hazardous Laboratory Chemicals Disposal Guide, Third Edition includes individual entries for over 300 compounds. The extensive list of references has been updated and includes entries for 15 pesticides commonly used in greenhouses. Emphasis is placed on disposal methods that turn hazardous waste material into non-toxic products. These methods fall into several categories, including acid/base neutralization, oxidation or reduction, and precipitation of toxic ions as insoluble solids. The text also provides data on hazardous reactions of chemicals, assisting laboratory managers in developing a plan of action for emergencies such as the spill of any of the chemicals listed.
