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Crónica del ejercicio de los recursos para infraestructura pública
La historia hay que vivirla, es decir: edificarla, día a día; con actos e inacciones, con palabras y silencios. Pero la historia, la que con el correr del tiempo gana ese carácter, y hasta con h mayúscula, no es un negocio individual, por más que en el presente algunas y algunos se empeñen, mera inercia que perdura del siglo XIX, en retratarse en los libros de manera personal, en calidad de históricos. ¿Qué historia hicimos en 2020, el año de la pandemia? ¿Cuál fue el papel que en su construcción jugamos? Porque, al finalizar 2021 hay consenso en que el año anterior tiene el carácter de histórico; no parece haber duda en que fue el inicio de un proceso que marcará a las suce...
Bioinformatics and Functional Genomics
Bioinformatics is a rapidly growing branch of science, which integrates the concepts of biology, engineering, mathematics and computer science in order to develop software tools. These tools are used in analyzing and interpreting biological data. Functional genomics is a sub-field of molecular biology, which uses the tools of bioinformatics to understand the diverse aspects of genes such as regulation of gene expression, DNA sequencing, gene transcription, protein-protein interactions, etc. There has been rapid progress in these fields and their applications are finding their way across multiple industries. This book is compiled in such a manner, that it will provide in-depth information about the theory and practice of bioinformatics and functional genomics. Students, researchers, experts, geneticists, biologists and biological engineers will benefit alike from this book.
Pediatric Medical Emergencies
The first volume in the "What Do I Do Now?: Emergency Medicine" series, Pediatric Medical Emergencies uses a case-based approach to cover common and important topics in the examination, investigation, and management of acutely ill children. The book addresses a wide range of topics including neonatal fever, pediatric sepsis, intussusception, and more, and is suited for emergency medicine providers and pediatricians.
The Spanish Flu Pandemic
Learn All About the Tragedies that Happened During the Time of the Spanish Flu Pandemic & Gain a Deeper Understanding of the Past! Did you know that the 1918 Spanish flu is the deadliest pandemic in history? It infected about one-third of the world's population and killed around 40 to 100 million people. Much like what's happening now as SARS-CoV-2 plagues the world, people all over the globe were required to wear masks, every non-essential establishment was closed down, and dead bodies overflowed in makeshift morgues. But, how much do you know about the Spanish Flu? Luckily for you, "The Spanish Flu Pandemic" by Elliot Frank lays out everything you need to know about the deadliest pandemic ...
Proteomic Methods in Neuropsychiatric Research
Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to cl...
Encyclopedia of Signaling Molecules
The second edition of this encyclopedia presents over 400 biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts. The molecules are described by recognized leaders in each molecule. The interactions of these single molecules in signal transduction networks will also be explored. This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike. Currently, there are more than 30,000 genes in human genome. However, not all the proteins encoded by these genes work equally in order to maintain homeostasis. Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities.
The Integrin Interactome
This volume provides the most cutting edge technologies related to the study of integrin activation and the characterization of their vast interactomes. Chapters detail protocols on experimental approached to quantify focal adhesion parameters, integrin activation, and the lateral interaction of integrins with transmembrane binding partners. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Integrin Interactome: Methods and Protocols aims to give the reader a multi-scale journey from single bonds inside protein structures to the function of these crucial adhesion receptors at a whole organism level in physiology and pathology.
