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Ion Channel Factsbook
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, sequence information, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, sequence information, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about pr...
Handbook of Ion Channels
The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce
Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models
Flow of ions through voltage gated channels can be represented theoretically using stochastic differential equations where the gating mechanism is represented by a Markov model. The flow through a channel can be manipulated using various drugs, and the effect of a given drug can be reflected by changing the Markov model. These lecture notes provide an accessible introduction to the mathematical methods needed to deal with these models. They emphasize the use of numerical methods and provide sufficient details for the reader to implement the models and thereby study the effect of various drugs. Examples in the text include stochastic calcium release from internal storage systems in cells, as well as stochastic models of the transmembrane potential. Well known Markov models are studied and a systematic approach to including the effect of mutations is presented. Lastly, the book shows how to derive the optimal properties of a theoretical model of a drug for a given mutation defined in terms of a Markov model.
Ion Mobility-Mass Spectrometry
Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields.
Ion-Exchange Membrane Separation Processes
Today, membranes and membrane processes are used as efficient tools for the separation of liquid mixtures or gases in the chemical and biomedical industry, in water desalination and wastewater purification. Despite the fact that various membrane processes, like reverse osmosis, are described in great detail in a number of books, processes involving ion-exchange membranes are only described in a fragmented way in scientific journals and patents; even though large industrial applications, like electrodialysis, have been around for over half a century. Therefore, this book is emphasizing on the most relevant aspects of ion-exchange membranes. This book provides a comprehensive overview of ion-e...
Ion Exchange
Ion Exchange, 2nd Edition is a totally revised and updated version of the highly popular Monograph for Teachers, first published by The Royal Society of Chemistry in 1975. It covers the practical application of ion exchange and the synthesis of organic ion exchange resins, which have spanned nearly 60 years of development since the pioneering work of Adams and Holmes in 1935. This book covers the theory, development, and application in considerable detail and describes the history of development of ion exchange materials and the advances in their utilization in industrial processes. Key applications in such areas as water purification, hydrometallurgy, and chromatography are described and su...
Book on Ion Exchange, Adsorption and Solvent Extraction
Water is a vital element for life. Each recognised form of life on earth, from the smallest microbes to the largest mammals, rely on water. But the amount of fresh water on the earth is limited. Due to industrialization, urbanization, and rapid growth of population; even this small amount of fresh water is compromised. This comprehensive book covers 14 review chapters on todays rapidly growing areas of ion exchange, adsorption and solvent extraction and provides an important resource for scientists, and researchers in the fields of environmental science, chemistry, nanotechnology, material science and engineering.
From Molecules to Networks
An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding th...
Ion Exchange in Analytical Chemistry
Analytical Chemistry, Volume 38: Ion Exchange in Analytical Chemistry provides a broad survey of the important role that ion exchange can and should play in chemical analysis. This book focuses on the plate-equilibrium theory of chromatography, which is less difficult theoretically than the mass-transfer theory. Organized into 11 chapters, this volume begins with an overview of the earliest recorded application of ion exchange. This text then examines how high temperature affects ion-exchange resins. Other chapters consider the exchange of ions between a solid ion-exchanging material and a solution, which is a typically reversible reaction. This book describes as well the relatively simple separations and other applications of ion exchange to analytical chemistry. The final chapter deals with the interesting nature of the metal complexes formed within the exchanger and describe the use of ion-exchange distribution studies to determine the stability and nature of complexes existing in the solution. This book is a valuable resource for analytical chemists.
