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Cancer Drug Resistance
This volume discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying quiescent blood-flow circulating cells; and single-cell characterization methods, such as mass cytometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Cancer Drug Resistance: Methods and Protocols is a valuable resource for all scientists and researchers who are looking to learn more about the latest developments in understanding and overcoming anticancer drug resistance.
Mental Illnesses
In the book "Mental Illnesses - Understanding, Prediction and Control" attention is devoted to the many background factors that are present in understanding public attitudes, immigration, stigma, and competencies surrounding mental illness. Various etiological and pathogenic factors, starting with adhesion molecules at one level and ending with abuse and maltreatment in childhood and youth at another level that are related to mental illness, include personality disorders that sit between mental health and illness. If we really understand the nature of mental illness then we should be able to not only predict but perhaps even to control it irrespective of the type of mental illness in question but also the degree of severity of the illness in order to allow us to predict their long-term outcome and begin to reduce its influence and costs to society. How can we integrate theory, research evidence, and specific ways to deal with mental illness? An attempt will be made in the last conclusive chapter of this volume.
Gallium Nitride-enabled High Frequency and High Efficiency Power Conversion
This book demonstrates to readers why Gallium Nitride (GaN) transistors have a superior performance as compared to the already mature Silicon technology. The new GaN-based transistors here described enable both high frequency and high efficiency power conversion, leading to smaller and more efficient power systems. Coverage includes i) GaN substrates and device physics; ii) innovative GaN -transistors structure (lateral and vertical); iii) reliability and robustness of GaN-power transistors; iv) impact of parasitic on GaN based power conversion, v) new power converter architectures and vi) GaN in switched mode power conversion. Provides single-source reference to Gallium Nitride (GaN)-based technologies, from the material level to circuit level, both for power conversions architectures and switched mode power amplifiers; Demonstrates how GaN is a superior technology for switching devices, enabling both high frequency, high efficiency and lower cost power conversion; Enables design of smaller, cheaper and more efficient power supplies.
Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.* Critical reviews of the previous year's literature in many topics of interest to medicinal chemists * Highlights major developments in medicinal chemistry * Includes a comprehensive set of cumulative indexes to easily locate topics in all published volumes
Behavior Change and Public Health in the Developing World
Focusing on universal public health issues, this book introduces students and practitioners to behaviour change theories and applications. It details experiences of successful programmes for the prevention and control of the world's biggest killers and explores health communication and social marketing strategies, learning theory, media advocacy and community development.
Novel Mechanisms of Memory
This book integrates discoveries from recent years to show the diversity of molecular mechanisms that contribute to memory consolidation, reconsolidation, extinction, and forgetting. It provides a special focus on the processes that govern functional and structural plasticity of dendritic spines. In nine chapters, new and important ideas related to learning and memory processes will be presented. Themes discussed include the role of AMPA receptors in memory, two signalling cascades involved in local spine remodelling and memory, the role of extracellular matrix proteins in memory, the regulation of gene expression and protein translation, and mechanisms of retrieval-induced memory modulation and forgetting. We believe that the study of these topics represents a great step toward understanding the complexity of the brain and the processes it governs.
Innovative Product Design and Intelligent Manufacturing Systems
This book gathers selected research articles from the International Conference on Innovative Product Design and Intelligent Manufacturing System (ICIPDIMS 2019), held at the National Institute of Technology, Rourkela, India. The book discusses latest methods and advanced tools from different areas of design and manufacturing technology. The main topics covered include design methodologies, industry 4.0, smart manufacturing, and advances in robotics among others. The contents of this book are useful for academics as well as professionals working in industrial design, mechatronics, robotics, and automation.
Arsenic Exposure and Health Effects IV
This collected volume of authoritative articles represents the state-of-the-art in arsenic research. Arsenic experts from around the world, participants in the Fourth International Conference on Arsenic Exposure and Health Effects organized by the Society of Environmental Geochemistry and Health in 2000, present their critical findings.A vital contribution to arsenic study and policy making, this volume examines the global impact of the toxin and discusses arsenic in the environment, mechanisms of arsenic metabolism and carcinogenesis, water treatment technology, and medical care. Arsenic Exposure and Health Effects offers informed, challenging insights into a highly important and controversial topic.
Egg Bioscience and Biotechnology
Egg Bioscience and Biotechnology provides a very focused look at the most recent advances in the study and value-added use of the bioactive components of eggs. This book focuses mainly on biologically active substances derived from egg components and their potential use. These include substances with anti-microbial, anti-adhesive, immunomodulatory, anti-cancer, anti-hypertensive, and anti-oxidant properties.
Current List of Medical Literature
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
