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A Phase II Trial to Evaluate the Combination of Pixantrone and Obinutuzumab for Patients with Relapsed Aggressive Lymphoma: Final Results of the Prospective, Multicentre GOAL Trial
  • Language: en

A Phase II Trial to Evaluate the Combination of Pixantrone and Obinutuzumab for Patients with Relapsed Aggressive Lymphoma: Final Results of the Prospective, Multicentre GOAL Trial

  • Type: Book
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  • Published: 2022
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  • Publisher: Unknown

Abstract: The prognosis of patients with relapsed diffuse large B-cell lymphoma (DLBCL) remains poor with current options. Here we prospectively evaluated the combination of pixantrone with obinutuzumab for up to six cycles for patients with relapsed or refractory DLBCL. Overall response rate (ORR) was the primary end-point. Sixty-eight patients were evaluated, median age was 75 years, median number of prior lines was three (range 1-10), 52 patients (76.5%) were diagnosed with DLBCL and 16 (23.5%) patients had transformed indolent lymphoma or follicular lymphoma (FL) IIIB. ORR was 35.3% for all and 40% for evaluable patients (16.6% complete response), median progression-free survival (PFS) a...

Lymphoma
  • Language: en
  • Pages: 11

Lymphoma

  • Type: Book
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  • Published: 2019
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  • Publisher: Unknown

None

Mantle Cell Lymphoma, An Issue of Hematology/Oncology Clinics of North America,E-Book
  • Language: en
  • Pages: 225

Mantle Cell Lymphoma, An Issue of Hematology/Oncology Clinics of North America,E-Book

This issue of Hematology/Oncology Clinics, Guest Edited by Dr. John P. Leonard, is devoted to Mantle Cell Lymphoma. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: Molecular pathogenesis of Mantle Cell Lymphoma; MCL and cell cycle dysregulation; Heterogeneity in MCL biology and outcomes; Watch and wait in mantle cell lymphoma; Limited stage mantle cell lymphoma; Initial and consolidation therapy for younger patients with MCL; Approach to the initial treatment of older patients with MCL; Current and future approaches to the use of minimal residual disease monitoring in the treatment of patients with MCL; Bruton’s Tyrosine Kinase inhibitors for treatment of Mantle Cell Lymphoma; BTKi resistance in MCL; Blastoid MCL; Allogeneic transplant and CAR-T cell therapy in MCL; Quality of life considerations and chronic therapy in management of patients with MCL; and Key clinical and translational research questions.

Anatomie der Sehnsucht
  • Language: de

Anatomie der Sehnsucht

  • Type: Book
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  • Published: 2018
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  • Publisher: Unknown

None

Cancer Research
  • Language: en
  • Pages: 736

Cancer Research

  • Type: Book
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  • Published: 2001-12
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  • Publisher: Unknown

None

Cancer Investigation
  • Language: en
  • Pages: 1046

Cancer Investigation

  • Type: Book
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  • Published: 1999
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  • Publisher: Unknown

None

Roshan Lall Gupta's Recent Advances in Surgery - 13
  • Language: en
  • Pages: 390

Roshan Lall Gupta's Recent Advances in Surgery - 13

Provides an up-to-date review of the surgical progress, Contains the topics important for the surgical practice, Comprises the study material, written, by eminent surgeons and experts in their fields, Includes the chapters on the evidence-based clinical guidelines which are extensively referenced, Proves to be incomparable value to postgraduate students and practicing surgeons. Book jacket.

Anticancer Research
  • Language: en
  • Pages: 1006

Anticancer Research

  • Type: Book
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  • Published: 1997
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  • Publisher: Unknown

None

Nucleoside Analogs in Cancer Therapy
  • Language: en
  • Pages: 494

Nucleoside Analogs in Cancer Therapy

  • Type: Book
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  • Published: 2021-10-28
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  • Publisher: CRC Press

Offering the most current and complete coverage of nucleoside analog activity in oncology and hematology, this single-source volume includes topics from pharmacology to previously unpublished clinical findings on the pivotal role of fludarabine, cladribine, and pentostatin in the management of diseases, such as chronic lymphocytic and hairy cell leukemia, non-Hodgkin's lymphoma, membranous nephropathy, and rheumatoid and psoriatic arthritis.

Major Companies of Europe
  • Language: en
  • Pages: 1112

Major Companies of Europe

  • Type: Book
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  • Published: 1994
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  • Publisher: Unknown

None