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Guidelines for Molecular Analysis in Archive Tissues
A huge amount of fixed and paraffin-embedded tissue is stored in every hospital. This is very precious material that can be used for translational research and for diagnostics. The molecular methods employed for analysis of these tissues are similar to the usual molecular biology and proteomics methods, but reliable results can be obtained only if specific steps are followed with great care. This book provides detailed and precise guidelines for molecular analysis of archive tissues and will serve as an invaluable aid for researchers and pathologists involved in translational research and diagnostics. Clear notes and explanations are included to simplify use of the protocols for the less experienced. The authors are a group of acknowledged experts who have developed the described methods and validated them within the European project "Archive Tissues: Improving Molecular Medicine Research and Clinical Practice - IMPACTS", which has involved 21 leading institutions in 11 countries.
Queer Brown Voices
In the last three decades of the twentieth century, LGBT Latinas/os faced several forms of discrimination. The greater Latino community did not often accept sexual minorities, and the mainstream LGBT movement expected everyone, regardless of their ethnic and racial background, to adhere to a specific set of priorities so as to accommodate a “unified” agenda. To disrupt the cycle of sexism, racism, and homophobia that they experienced, LGBT Latinas/os organized themselves on local, state, and national levels, forming communities in which they could fight for equal rights while simultaneously staying true to both their ethnic and sexual identities. Yet histories of LGBT activism in the 197...
The Rudys of God's House and Related Families
Descendants of immigrant Martin Rudy, born in Switzerland 1739. He arrived in Pennsylvania in 1751.
Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges
Recent advances in the understanding of the biological basis of pediatric soft-tissue and bone tumors, especially owing to the advent of “omics” technologies, have led to an exponential increase in the current knowledge on the genetic and cellular patho-mechanisms that drive these diseases. This offers the unprecedented opportunity to develop and implement targeted therapies such as monoclonal antibodies, small molecules, oncolytic viruses, and immunotherapies in standard and/or personalized treatment regimens. However, to date only a few examples document a successful translation of discoveries from the bench to the bedside. Recent international expert congresses further emphasize the u...
Bali
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The Pennsylvania Relations of Dwight D. Eisenhower
Dwight David Eisenhower was born in 1890 in Denison, Texas. His parents were David Jacob Eisenhower and Ida Elizabeth Stover. Ancestors, descendants and relatives lived mainly in Pennsylvania, Kentucky, Tennessee, Kansas and Colorado.
Bali Marco Polo Pocket Guide
Experience Bali, Lombok and the Gili Islands with this up-to date, authoritative guide, packed with Insider Tips. Discover Bali's beaches, volcanic landscapes, rice terraces and more with this handy, pocket-sized guide which includes a pull-out map.
The Schales Book
Caspar Schales (b.1817), son of Johaness Schales (b.1785) and Maria Elisabeth Lindt, immigrated from Germany to Perry County, Indiana in 1838, and married Charlotte Foster in 1845. His parents and their youngest son, Jacob, immigrated to join Caspar in 1846. Descendants lived in Indiana, Ohio, Minnesota, Arkansas, Missouri, Texas, New Mexico, California and elsewhere. Includes ancestors to the early 1700s and their descendants in Germany.
