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This updated and revised 2nd edition of "Drug Benefits and Risks" is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs, but in this context also highlighting the social impact which drugs have in modern societies. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose, the book covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases; the book gives guidance on how doctors should act so that drugs can be used effectively and safely; and it encourages the rational use of drugs in society.This publication brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.
First multi-year cumulation covers six years: 1965-70.
This is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs but in this context also the social impact which drugs have in modern societies is highlighted. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose the book * Covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases * Gives guidance on how doctors should act so that drugs can be used effectively and safely * Encourages the rational use of drugs in society This book brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.
Prepared in collaboration with the Medical Library Association, this completely updated, revised, and expanded edition lists classic and up-to-the-minute print and electronic resources in the health sciences, helping librarians find the answers that library users seek. Included are electronic versions of traditionally print reference sources, trustworthy electronic-only resources, and resources that library users can access from home or on the go through freely available websites or via library licenses. In this benchmark guide, the authors Include new chapters on health information seeking, point-of-care sources, and global health sources Focus on works that can be considered foundational or essential, in both print and electronic formats Address questions librarians need to consider in developing and maintaining their reference collections When it comes to questions involving the health sciences, this valuable resource will point both library staff and the users they serve in the right direction.
Pharmacodynamics is the oldest in vitro element of pharmacology and the youngest in vivo element. However, over the last decade there has been significant progress in understanding the kinetics of drug action in vivo and pharmacodynamics now ranks with pharmacokinetics in the content of clinical pharmacology journals. The purpose of this book is to link theory and practice of in vivo pharmacodynamic studies. This presents a major challenge due to the multi-faceted nature of the kinetics of drug actions. The first step involves identification of those effects which represent the actions of a drug using mathematical models in combination with classical receptor theory. Subsequently, these effects must be quantified in a precise and reproducible manner and the pharmacokinetcs of the drug and its active metabolites must be accurately described. Finally, realistic models must be developed which identify the site of action and can describe and predict the time course of drug action under physiological and pathological conditions. As in the development of most sciences the theory is in advance of the practice.