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Cancer Immunotherapy
This chapter describes the types of adjuvants that are being investigated as potential cancer adjuvant candidates and those that are currently being used in vaccines against certain cancers.
Cancer Immunotherapy
There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational...
The Hill and Beyond
The variety that is children's television drama is recalled in this book; shows such as: "Grange Hill"; "Stig of The Dump"; "The Railway Children"; "The Magician's House"; "The Chronicles of Narnia"; and "The Box of Delights". It lists entries on every British-made children's drama to have been shown on UK screens since 1950. Critical appraisals assess the kind of stories told for children, along with all the technical data and trivia. Programmes from the BBC and ITV are assessed, whether they were adaptations of literary classics or new, contemporary dramas, adventure, fantasy or science fiction.
Power, Knowledge and Feminist Scholarship
Feminist scholarship is sometimes dismissed as not quite ‘proper’ knowledge – it’s too political or subjective, many argue. But what are the boundaries of ‘proper’ knowledge? Who defines them, and how are they changing? How do feminists negotiate them? And how does this boundary-work affect women’s and gender studies, and its scholars’ and students’ lives? These are the questions tackled by this ground-breaking ethnography of academia inspired by feminist epistemology, Foucault, and science and technology studies. Drawing on data collected over a decade in Portugal and the UK, US and Scandinavia, this title explores different spaces of academic work and sociability, conside...
The Inflammasome
This Methods in Molecular Biology book offers methods for studying inflammasome function, including generation of inflammasome stimuli, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, plus lab protocols, material lists and tips.
7 Years of Camera Shake
As humans, we are drawn to predators like no other group of animals. They are the epitome of form and function, and have a level of perfection that we revere. In 2009, wildlife expert, conservationist and photographer David Plummer was diagnosed with Parkinson’s disease. Rather than let it defeat him, he was galvanised to grab life by the horns and achieve the perfect wildlife shot. Over the next seven years, he did much more than that. The result is this breathtaking collection of over 200 of his best and favourite photographs of exotic and wild animals in their natural habitats. To capture them, David travelled to some of the most remote and stunning locations across the world, from Afri...
Zed and the Cormorants
Zed and her family move unwillingly from London to a village in Cornwall, in an attempt to support her mother's mental health. Dad says they need a fresh start, but no one's asked Zed what she thinks. She knows she'll never fit into her new school, or make any friends, let alone find someone special. At this rate she'll be lucky to find a phone signal... Maybe their new home will help with Mum's depression, and keep Zed's sister Amy away from her dropout boyfriend, but why does it have to be so remote? Why has the boathouse been locked up for seventy years? Why do the birds living by the estuary fill her with such dread? And what do they WANT? Gradually the family fall apart, and it is only when Zed realises that the local cormorants are playing a part in the disasters that consume them, in revenge for an ancient wrong, that she and Amy start working together to find a solution and call a truce.
