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Reducing Adverse Effects of Cancer Immunotherapy
Chemotherapy and/or radiotherapy remain the main treatment options for most cancers. However, cancer treatment is associated with numerous adverse effects, including fatigue, stress, hair loss, pain, nausea, vomiting, anemia, altered immune system, oral and intestinal mucositis, which significantly affect patients' quality of life. In addition, the adverse effects may be associated with additional costs, morbidity, and mortality that affect various aspects of the patient's life, including physical health and emotional state. The management and reduction of adverse effects are extremely important and complex and are primarily aimed at providing comfort to the patient during chemotherapy treatment. In addition, it is important to note that in some cases, the severity of side effects associated with cancer treatment may result in the need to reduce the dose, which in turn may be associated with a reduction in the therapeutic efficacy. In view of this, the identification of new options aimed at alleviating the side effects and increasing the tolerability of chemotherapy is necessary to ensure the quality of life of cancer patients.
Handwriting
This book has the primary goal of presenting and discussing some recent advances and ongoing developments in the Handwritten Text Recognition (HTR) field, resulting from works done on different HTR-related topics for the achievement of more accurate and efficient recognition systems. Nowadays, there is an enormous worldwide interest in HTR systems, which is mostly driven by the emergence of new portable devices incorporating handwriting recognition functions. Others interests are the biometric identification systems employing handwritten signatures, as well as the requirements from cultural heritage institutions like historical archives and libraries in order to preserve their large collecti...
Handbook of Low-Level Laser Therapy
Low-Level Laser Therapy (LLLT) also known as photobiomodulation is almost 50 years old, and recently has been getting increasing acceptance from the scientific, medical, and veterinary communities. Discoveries are constantly being made about the cellular and molecular mechanisms of action, the range of diseases that can be treated is also rising, and home use LED devices are becoming common. This book compiles cutting-edge contributions from the world’s leading experts in Photobiomodulation and LLLT. Chapters cover general concepts, mechanisms of action, in vitro studies, pre-clinical animal studies, veterinary applications and a wide range of clinical topics. Edited by Michael Hamblin from Massachusetts General Hospital and Harvard Medical School, aided by two prominent researchers (Marcelo Sousa and Tanupriya Agrawal), this book will appeal to anyone involved in the basic science, translational aspects and clinical applications of LLLT.
Esteja, viva, permaneça 100% Presente
Ao longo de uma rotina estressante e desmotivadora, vemos nossos sonhos se tornarem distantes e, muitas vezes, não sabemos como alcançá-los. Essa sensação de derrota, no entanto, é uma armadilha que criamos para nós mesmos e que nos impede de ter clareza sobre qual é a nossa meta, e mais, nos impossibilita de focar as ações necessárias para conquistar o resultado que queremos e merecemos. Contudo, há um modo de jogar o jogo de outra maneira. O sucesso é treinável e, neste livro, você aprenderá os 5 passos para desenvolver alta performance em todas as áreas da sua vida e começará a construir o seu novo futuro antes de chegar aos capítulos finais. Neste livro, você aprenderá a: •Entrar em ação imediatamente!; •Fazer uma autoanálise e tomar a melhor decisão para você; •Alinhar os seus propósitos e construir uma mentalidade favorável para se livrar das armadilhas que impedem o seu sucesso; •Treinar para se tornar imbatível; •Ter consistência e se tornar um gigante; •Viver 100% presente e ter alta performance sempre.
Doing Business 2012
Ninth in a series of annual reports comparing business regulations in 183 economies, Doing Business 2012 measures regulations affecting 11 areas of everyday business activity: starting a business dealing with construction permits employing workers registering property getting credit protecting investors paying taxes trading across borders enforcing contracts closing a business getting electricity The report updates all indicators as of June 1, 2011, ranks countries on their overall "ease of doing business", and analyzes reforms to business regulation identifying which countries are strengthening their business environment the most. Doing Business 2012 includes a new set of indicators on the ...
Doing Business 2010
The seventh in a series of annual reports investigating the regulations that enhance business activity and those that constrain it, 'Doing Business' presents quantitative indicators on business regulations and the protection of property rights that can be compared across 183 economies--from Afghanistan to Zimbabwe--and over time. Regulations affecting 10 stages of a business's life are measured: starting a business, dealing with construction permits, employing workers, registering property, getting credit, protecting investors, paying taxes, trading across borders, enforcing contracts and closing a business. Data in 'Doing Business 2010' are current as of June 1, 2009. The indicators are used to analyze economic outcomes and identify what reforms have worked, where and why.
Evolutionary Transitions to Multicellular Life
The book integrates our understanding of the factors and processes underlying the evolution of multicellularity by providing several complementary perspectives (both theoretical and experimental) and using examples from various lineages in which multicellularity evolved. Recent years marked an increased interest in understanding how and why these transitions occurred, and data from various fields are providing new insights into the forces driving the several independent transitions to multicellular life as well as into the genetic and molecular basis for the evolution of this phenotype. The ultimate goal of this book is to facilitate the identification of general and unifying principles and mechanisms.
TEMAS EM EDUCAÇÃO: Olhares Interdisciplinares, Reflexões e Saberes – Volume 1
Esta obra tem como premissa um novo olhar sobre os diversos temas em Educação diante do conhecimento, propõe uma mudança de atitude em busca do contexto do processo de ensino, ou seja, estabelece uma aprendizagem integral. Seu objetivo é construir um conhecimento global com olhares interdisciplinares por meio das reflexões e saberes e romper com os limites das disciplinas, fazendo com que os alunos compreendam a aplicabilidade dos conteúdos em diferentes contextos da sociedade, estabelecendo um vínculo com a realidade, ultrapassando uma abordagem puramente teórica e reducionista. Enfim, a obra é um convite ao pensamento reflexivo, abrangente e contextual em torno da necessidade real de análise dos diversos temas e aspectos em Educação.
