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Contraceptive Research, Introduction, and Use
As the first real contraceptive innovation in over 20 years, and as a long-acting method requiring clinical intervention for application and removal, the implantable contraceptive Norplant has raised a wide range of issues that could offer valuable lessons about the problems to be addressed if other new contraceptive technologies are to enter the marketplace. In April 1997 an Institute of Medicine workshop on implant contraceptives reviewed newly available data on Norplant's efficacy, safety, and use; identified lessons to be learned about the method's development, introduction, use, and market experience; and explored approaches to developing and introducing new contraceptives based on those lessons. This resulting book contains an examination of Norplant's efficacy and safety, its user populations, training for insertion and removal, consumer perspectives (quality of care, informed decisionmaking, and consumer involvement), and new approaches to contraceptive development and introduction. An appendix contains summaries of 17 workshop presentations.
Biodegradable and Delivery Systems for Contraception
There are problems with recently-developed injectable or implant contraceptives which provide too much drug at 1 time and which are limited to use of only a few compounds of specific chemistry. Delivery systems which have to be removed also provide a problem. Research is underway to develop a biodegradable delivery system based on polymers. These systems could deliver the drug either by a mechanism of drug diffusion through the polymer, delivery as the polymer matrix biodegrades, or a combination of the 2 methods. These systems could make use of any number of synthetic or natural drugs. Current research on suitable polymer materials and release mechanisms is reviewed. The systems do seem to have the potential of expanding the range of available parenteral depot contraceptives. Absolute clinical data are not yet available.
Contraceptive Research and Development
The "contraceptive revolution" of the 1960s and 1970s introduced totally new contraceptive options and launched an era of research and product development. Yet by the late 1980s, conditions had changed and improvements in contraceptive products, while very important in relation to improved oral contraceptives, IUDs, implants, and injectables, had become primarily incremental. Is it time for a second contraceptive revolution and how might it happen? Contraceptive Research and Development explores the frontiers of science where the contraceptives of the future are likely to be found and lays out criteria for deciding where to make the next R&D investments. The book comprehensively examines tod...
Contraception: Your Questions Answered6
Includes information about contraception methods, effectiveness, mechanisms, side-effects and complications.
Bioresorbable Osmotic Pump for Long-term Contraception
Hyaluronic acid was selected for the osmotic engine, and our early work confirmed its potential for linear expansion and for overcoming the high hydraulic pressure of the viscous formulation. This fully bioresorbable, zero-order release osmotic pump system has the potential to be an impactful long-term drug delivery platform device for contraception, as well as other diseases that affect the global population where drug adherence is necessary for efficacy.
The Handbook of Contraception
This book presents an up-to-date and comprehensive review of female contraception, offering an extensive overview of contraception types, including oral, injectable, emergency, and various cervical barrier contraceptives. It also discusses behavioral and sterilization methods of contraception as well as the clinical effectiveness, advantages, disadvantages, side effects, and mechanisms of action of each method. Now in its fully revised and expanded third edition, this text includes seven new chapters that address specific clinical issues that healthcare providers face daily. These issues include patients with medical problems, perimenopausal women, the adolescent population, post-pregnancy p...
