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Cochlear and Brainstem Implants
Today cochlear implants are the most successful of all prostheses of the nervous system. They are used in individuals who are deaf or suffer from a severe hearing deficiency caused by loss of cochlear hair cells. Auditory brainstem implants provide stimulation of the cochlear nucleus and are used in patients with an auditory nerve dysfunction, a deformed cochlea which does not allow cochlear implantation, or traumatic auditory nerve injury. In this volume different aspects of cochlear implantation such as the role of neural plasticity, the interaction with the development of the auditory system, and the optimal time of implantation in children (sensitive periods) are discussed in detail. Fur...
Cochlear Implants
This book is a comprehensive illustration of content covering cochlear implants' past, present, and future perspectives. It delves into history, about how the first implant was conceived around 50 years ago and how modern cochlear implants provide better hearing and speech discrimination with the evolution of technology. This book discusses the basic working principles of cochlear implants, along with a review of their clinical use. The book also elaborates upon the various surgical techniques authored by clinicians who are pioneers. This book covers various important topics such as implantation in abnormal cochleas, bilateral implantation, implanting with acoustic and electric stimulation, and re-implantation. The book guides selecting the suitable candidates, describing preoperative evaluation and imaging techniques. This book will be an invaluable source of guidance for ENT surgeons, Audiologists, and Neurologists, along with undergraduate and postgraduate students in Audiology and ENT.
Regenerative Medicine for the Inner Ear
The research described in this book represents important steps toward understanding the development of inner ear medicine and new perspectives in regenerative medicine, including efficacy in cochlear implants and various other treatments. The book depicts the mechanisms that underlie inner ear diseases, their experimental models, and proposals for new strategies to treat their symptoms. As well, the exciting future prospects for dealing with the very common problem of inner ear diseases are explained. These disorders occur among many people and include sensorineural hearing loss (SNHL), sudden deafness, senile deafness, noise-induced deafness, tinnitus, dizziness–vertigo, and Ménière’s...
Cochlear Implants: Adult and Pediatric, An Issue of Otolaryngologic Clinics
Clinical information for Otolaryngologists is provided in topics that include: Imaging and Anatomy; Genetics of Hearing Loss, Testing and Relevance to Cochlear Implantation; Candidacy Evaluation, Medical and Surgical Considerations, expanding criteria in Children; Surgical Technique and Accepted Variations in Children; Bilateral Cochlear Implantation; Implanting Obstructed and Malformed Cochleae; Device Programming NRT, NRI, Streamlined programming; Cochlear Implants and Music; Rehabilitation and Educational Considerations; Outcomes and Variables Affecting Outcomes; Language Development and Cochlear Implantation; New Frontiers in Cochlear Implantation, electroacoustic, hearing preservation, etc; Revision Cochlear Implantation in Children; and Current and Future Device Options.
Orotic Acid
This volume reviews a series of different publications dealing with orotic acid. Orotic acid was isolated from cow's milk 75 years ago by Biscaro and Belloni in Italy. Fifty years later again Italian scientists described the growth-promoting activity of orotic acid in vitamin B -deficient animals. 12 Orotic acid is the precursor of pyrimidine nucleotides which are involved in many biochemical reactions: UTP and CTP, as substrates for RNA polymerase, and UDP sugars, as substrates for carbohydrate containing macromolecules, e.g. glycogen, glycoproteins and glycolipids. The biosynthesis of these pyrimidines is well regulated. Disturbance of the biosynthetic pathway or trapping of individual pyr...
Implantable Neural Prostheses 1
Significant progress has been made in the development of neural prostheses to restore human functions and improve the quality of human life. Biomedical engineers and neuroscientists around the world are working to improve design and performance of existing devices and to develop novel devices for artificial vision, artificial limbs, and brain–machine interfaces. This book, Implantable Neural Prostheses 1: Devices and Applications,ispart one of a two-book series and describes state-of-the-art advances in techniques associated with implantable neural prosthetic devices and their applications. Devices covered include sensory prosthetic devices, such as visual implants, cochlear implants, auditory midbrain implants, and spinal cord stimulators. Motor prosthetic devices, such as deep brain stimulators, Bion microstimu- tors, the brain control and sensing interface, and cardiac electro-stimulation devices are also included. Progress in magnetic stimulation that may offer a non-invasive approach to prosthetic devices is introduced. Regulatory approval of implantable medical devices in the United States and Europe is also discussed.
