Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Bulletin
None
Combinatorial Methods in Topology and Algebra
Combinatorics plays a prominent role in contemporary mathematics, due to the vibrant development it has experienced in the last two decades and its many interactions with other subjects. This book arises from the INdAM conference "CoMeTA 2013 - Combinatorial Methods in Topology and Algebra,'' which was held in Cortona in September 2013. The event brought together emerging and leading researchers at the crossroads of Combinatorics, Topology and Algebra, with a particular focus on new trends in subjects such as: hyperplane arrangements; discrete geometry and combinatorial topology; polytope theory and triangulations of manifolds; combinatorial algebraic geometry and commutative algebra; algebraic combinatorics; and combinatorial representation theory. The book is divided into two parts. The first expands on the topics discussed at the conference by providing additional background and explanations, while the second presents original contributions on new trends in the topics addressed by the conference.
Primary Aldosteronism
Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene – KCNJ5 – in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more.
Microcirculation in Cardiovascular Diseases
This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervent...
From Basic Immunology to Immune-Mediated Demyelination
Morphological, physiological and pathological evidence demonstrates that ner vous and immune systems interact not only in maintaining brain homeostasis, but also in causing neurological diseases. The studyofthese interactions repre sents the basis on which neuroimmunologyhas grown during the years. At pre sent, several neurological diseases are recognized to be caused by a derange ment of the immune system in either its regulatory or effector functions. The main scope ofthis book, to discuss how an unbalanced immune system maylead to immune-mediated neurological diseases, is achieved in three parts. The first part provides an overview on how the immune system works. This is propaedeu...
Advances in Multiple Sclerosis and Experimental Demyelinating Diseases
Controversy still exists regarding how early disease-modifying agents (DMA) should be commenced and whether all patients with relapsing-remitting MS should in fact be treated. To answer these questions, it is also important to know the natural history of the disease. MS affects nearly 400,000 people in the United States. With their novel, multifaceted approach to basic science, the authors of this book offer help to clinicians and hope to patients.
Emergency Surgical Management of Colorectal Cancer
This volume provides an overview of the current evidence-based medical and surgical practice in emergency conditions in colorectal cancer patients. It offers a multidisciplinary perspective, taking into account the specific characteristics of colorectal cancer patients, the necessary pre-operative assessment, the endoscopic and radiological management, and the surgical treatments. Each chapter is supplemented with tables, figures, key-point boxes, schematic representations, and decision-making trees that serve as easy-to-use tools to apply in the different scenarios requiring acute care. Recommendations for best practice and the main reference articles are included for each topic, as well as numerous illustrated clinical cases with cilnical and empirical evidence regarding the surgical management of colorectal cancer. Specific technical aspects of the different surgical interventions and approaches (e.g., open surgery, laparoscopy, and robotics) are also detailed. This book is intended for residents and emergency surgeons, as well as all practictioners who treat colorectal cancer patients, such as gastroenterologists, oncologists, and radiologists.
Temporomandibular Disorders
An authoritative and comprehensive account of the assessment and conservative management of temporomandibular disorders. Recent emphasis has been on 'evidence-based practice' at the expense of the clinical reality which should also take account of clinician expertise and patient preference. A sound research base is not always available. This text addresses the clinical reality of having to make decisions using other sources of knowledge in the absence of a comprehensive scientific rationale. It advocates clinical and evidence-informed practice - an approach which acknowledges the value of clinician experience and expertise as well as research findings. Compiled and edited by two highly regarded and experienced practitioners, researchers and authors who have already published many books and journal articles in the field. With contributions from a mix of 28 internationally-based clinicians and clinician-researchers allowing the text to highlight both current best evidence and clinicians' expertise and experience. Contributors include talented young clinicians as well as established experts in orthopaedic physiotherapy and world-level expert researchers.
Gene Therapy Protocols
Efforts in gene therapy have grown dramatically in recent years. Basic research as well as clinical activity have made exciting progress and are beg- ning to offer renewed hope that gene therapy may be able to deliver novel approaches for the treatment of inherited as well as such acquired diseases as cardiovascular disease and cancer. With the sequencing of the human genome complete, we now have a comprehensive catalog of genes that further expands the potential role of gene therapy into such new fields as tissue engineering. Central to gene therapy is the process of gene transfer; thus, advances in the technology of gene transfer are at the heart of this field’s progress. Numerous technologies, based on a variety of methods (e.g., viral-mediated, physical/ chemical), have been developed to achieve gene transfer. Some of the earliest methods, such as recombinant retroviruses, are still widely used, have undergone significant improvements, and have given rise to new vectors based on lentiviruses.
