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This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders. Tackling the topic in a systematic manner, the book starts with an introduction to cardiometabolic risk and its clinical relevance, comparing emergent and classical biomarkers. It then goes on to discuss cardiometabolic risk biomarkers in a range of diseases, including diabetes, ischemic stroke and neurodegenerative disorders. Biomarkers of Cardiometabolic Risk, Inflammation and Disease is aimed at doctors specializing in internal medicine, neurology, cardiology, rheumatology, nephrology or endocrinology and will also be of interest to GPs, trainee doctors and clinical and basic researchers working on cardiovascular and autoimmune disorders.
The book aims at a readership of both economists and historians. Beyond the well-known Weberian thesis concerning the role of Protestantism in the development of capitalism, monastic economies are studied to assess their impact on the religious patterns of economic behavior. Those issues are discussed in the frame of key economic concepts such as rationality, state intervention, networking, agency, and governance. The book includes essays concerning Byzantine, Ottoman and modern South-Eastern Europe, and early modern Western Europe. Survival and continuity of the monastic wealth is considered as an example of successful handling of real estate transactions, flows of funds, and contacts with financial institutions. Moreover, the book focuses on the economic impact of the privileged relations of monasticism with the secular powers. Finally, the question is raised how the monastic economy (still) matters in the contemporary world.
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This thesis focuses on disease activity in clinically isolated syndrome (CIS) and newly diagnosed relapsing remitting multiple sclerosis (RRMS). The papers are based on data from 41 patients in a prospective longitudinal cohort study. All patients were untreated at baseline. Age- and sex-matched healthy controls (n=22) for blood and cerebrospinal fluid (CSF) samples were recruited from blood donors. Paper I evaluated the prognostic value of baseline levels of CXCL1, CXCL8, CXCL10, CXCL13, CCL22, neurofilament light chain (NFL), neurofilament heavy chain, glial fibrillary acidic protein, chitinase-3-like-1 (CHI3L1), matrix metalloproteinase-9 (MMP-9) and osteopontin in CSF in relation to dise...
Geriatric Psycho-Oncology is a comprehensive handbook that provides best practice models for the management of psychological, cognitive, and social outcomes of older adults living with cancer and their families. Chapters cover a wide range of topics including screening tools and interventions, psychiatric emergencies and disorders, physical symptom management, communication issues, and issues specific to common cancer sites. A resource section is appended to provide information on national services and programs. This book features contributions from experts designed to help clinicians review, anticipate and respond to emotional issues that often arise in the context of treating older cancer patients. Numerous cross-references and succinct tables and figures make this concise reference easy to use. Geriatric Psycho-Oncology is an ideal resource for helping oncologists and nurses recognize when it may be best to refer patients to their mental health colleagues and for those who are establishing or adding psychosocial components to existing clinics.
Throughout the local Bronze and Iron Age, European and Mediterranean societies appear to have been involved in complex systems of exchange networks which invariably affected local customs and historical developments. Archaeological evidence suggests social and economic phenomena, cultural expressions and technological skills stemmed from multifaceted encounters between local traditions and external influences. Examples of cultural openness and transcultural hybridisation seem to be more of a norm than an exception. The articles in the volume explore the dynamic relationship between regionally contextualized transformations and inter-regional exchange networks. Particular effort has been put in approaching the issue in a multidisciplinary perspective. Continental Europe and the Mediterranean may be characterized by specific development and patterns of relations, but the authors draw attention to how those worlds were not alien to each other and illustrate how common interpretative tools can be successfully applied and a comprehensive approach including both zones adopted.