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Drug-Drug Interactions
Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on:key interplay between transporters and enzymes
Fiscal Adjustment and Income Inequality
We combine state-level fiscal data with household survey data to assess the links between sub-national fiscal policy and income inequality in Brazil over the period 1995-2011. The results indicate that a tighter fiscal stance at the sub-national level is not associated with a deterioration in inequality measures. This finding contrasts with the conclusions of several papers in the burgeoning literature on the effects of fiscal consolidation on inequality using national data for OECD economies. In addition, we find that a tighter stance is typically positively associated with a measure of “shared prosperity”. Hence, our results caution against extrapolating policy implications of the literature focusing on advanced economies to other settings.
Portuguese Studies Review, Vol. 16, No. 2
This issue of the Portuguese Studies Review presents essays by Glenn J. Ames, N. Shyam Bhat, Sim Yong Huei, Maria Cristina Moreira and Sérgio Veludo, Ana Mónica Fonseca and Daniel Marcos, Reinaldo Francisco Silva, Filipa Fernandes, and Robert Simon. The topics covered range from colonial Christian proselytization to the political interaction between Portuguese Goa and the Karnataka, war and diplomacy in the Estado da India (1707-1750), Portuguese military uniforms in the nineteenth century, perceptions of the United States through immigrant eyes, French and German military support for Portugal in 1958-1968, the politics of water supply, and the poetics of Herberto Helder.
Drug-Drug Interactions
Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives. Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on: key interplay between transporters and enzymes in drug metabolism and drug interactions the integral role of pharmacogenetics in metabolism-based drug-drug interactions in vivo - in vitro correlations (reversible, mechanism-based inhibition, induction) in silico approaches enabling structure-activity and structure-function studies high-throughput screening and GLP methods for evaluating drug interactions in vitro the use of transgenic animal models to evaluate drug interactions Providing helpful case examples and computer-aided modeling, Drug-Drug Interactions is filled with over 200 invaluable tables, equations, and figures to clarify key concepts, and incorporates critical new updated information.
Management of Multimedia Networks and Services
We are delighted to present the proceedings of the 8th IFIP/IEEE International Conference on Management of Multimedia Networks and Services (MMNS 2005). The MMNS 2005 conference was held in Barcelona, Spain on October 24–26, 2005. As in previous years, the conference brought together an international audience of researchers and scientists from industry and academia who are researching and developing state-of-the-art management systems, while creating a public venue for results dissemination and intellectual collaboration. This year marked a challenging chapter in the advancement of management systems for the wider management research community, with the growing complexities of the “so-ca...
An Appraisal of the Status of Chagas Disease in the United States
This title critically reviews old and new literature, help to create greater awareness of the disease in the US and helps in the evaluation of certain epidemiological and public health issues. During the first half of the 20th century, Chagas disease was assumed to be absent from the U.S. and considered an exotic disease, until the first two indigenous cases were discovered, almost simultaneously, in Texas, 1955. Since that time four indigenous cases have been documented in several places in the country. Although the disease is still considered uncommon in the US, this disease is not longer an exclusive Latin American illness. Physicians in the US are often unaware of the characteristics of the diseases, and are likely overlooking locally acquired cases. The influx of an estimated 300,000 Latin American immigrants with the Chagas parasite means that there is an urgent need for physicians and public health officials to become aware. - Helps to create greater awareness of Chagas disease in the USA - Helps to evaluate epidemiological and public health issues - Facilitates accurate and necessary future public health interventions
Regional Economic Outlook, April 2016, Sub-Saharan Africa
Economic growth in sub-Saharan Africa as a whole has fallen to its lowest level in 15 years, though with large variation among countries in the region. The sharp decline in commodity prices has severely strained many of the largest economies, including oil exporters Angola and Nigeria, and other commodity exporters, such as Ghana, South Africa, and Zambia. At the same time, the decline in oil prices has helped other countries continue to show robust growth, including Kenya and Senegal. A strong policy response to the terms-of-trade shocks is critical and urgent in many countries. This report also examines sub-Saharan Africa’s vulnerability to commodity price shocks, and documents the substantial progress made in financial develop, especially financial services based on mobile technologies.
A Christmas Carol
Instead of memorizing vocabulary words, work your way through an actual well-written novel. Even novices can follow along as each individual English paragraph is paired with the corresponding Portuguese paragraph. It won't be an easy project, but you'll learn a lot.
