Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Developments in T Cell Based Cancer Immunotherapies
This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when adoptively transferred back to the patients. Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents. Furthermore, the revolutionary role of checkpoint inhibitors and their potential in combination with other immunotherapeutic approaches or with standard chemo and radiation therapy are extensively discussed.
Cancer Stem Cells in Solid Tumors
The “cancer stem cell” hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs). While the idea of cancer stem cells has been around for more than a hundred years, evidence from the fields of hematology and cancer biology has now demonstrated the critical role of stem cells in hematological malignancies and suggested that these same mechanisms are also central to the initiation, progression, and treatment of solid cancers. Clinical and experimental studies have shown that CSCs exhibit many classical properties of normal stem cells, including a high self-renewal capacity and the ability to generate heterogeneous lineages; the requ...
Hematology E-Book
Hematology, 6th Edition encompasses all of the latest scientific knowledge and clinical solutions in the field, equipping you with the expert answers you need to offer your patients the best possible outcomes. Ronald Hoffman, MD, Edward J. Benz, Jr., MD, Leslie E. Silberstein, MD, Helen Heslop, MD, Jeffrey Weitz, MD, John Anastasi, MD, and a host of world-class contributors present the expert, evidence-based guidance you need to make optimal use of the newest diagnostic and therapeutic options. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're...
Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma
This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers.
FRONTIERS IN ONCOLOGY: EDITOR’S PICK 2021
We are pleased to introduce the 2021 Frontiers in Oncology: Editor’s Pick collection, showcasing articles stimulating interest in the field, carefully selected by our Field Chief Editor, Prof. Giuseppe Giaccone, of Weill Cornell Medicine. With this ebook we aim to highlight and disseminate important findings across the domains of cancer research, capturing the multidisciplinary and inclusive approach our journal takes towards advancing the field of oncology and supporting the global effort towards improved quality of life and patient survival. 2021 was a year which saw our highest journal impact factor yet, international community growth, and a record-breaking number of articles to choose from. We wish to elevate the contributions made by authors, encourage readership and innovation through our open-access philosophies, and thank our Editorial Board for their continued hard work and collaboration.
Memory T Cells
Immunological memory has fascinated microbiologists and immunologists for decades as one of the new frontiers to conquer to better understand the response to pathogens, cancer and vaccination. Over the past decade, attention has turned to the intrinsic properties of the memory T cells themselves, as it has become clear that the eradication of both infected cells and tumors requires T cells. This book is an attempt to capture the wave of discoveries associated with these recent studies. Its chapters represent a wide collection of topics related to memory T cells by laboratories that have invested their skills and knowledge to understand the biology and the principles upon which memory T cells are generated, maintained and expanded upon re-encounter with antigen. Ultimately, these studies are all aimed at a better understanding of the function of memory T cells in protection against disease.
Tumor-Associated Antigens
The first comprehensive and most recent overview of the topic, this ready reference and handbook reviews current knowledge of TAAs, their subclasses, and pinpoints their application areas in medicine. In addition, it emphasizes target identification procedures, the need for an accurate and thorough analysis of the function of TAAs, and the validation of those in clinical settings. The whole is rounded off with an overview of currently approved therapeutic antibodies. The result is a must-have for biologists and oncologists in science, clinics and industry.
Transfusion Medicine, An Issue of Hematology/Oncology Clinics of North America
This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Edward Snyder and Eric A. Gehrie, with Consulting Editors George P. Canellos and H. Franklin Bunn, will focus on Transfusion Medicine. Topics include, but are not limited to, Pathogen Reduction, Transfusion Reactions-Infectious Complications, Txn Rxn-Non-Infectious Complications, Iron Deficiency and Teen Blood Donors, Advances in RBC Serology, Advances in Immunotherapy, Therapeutic Monoclonal Antibody Effect on RBC Compatibility Testing, Cell Therapy-New Regulations and Standards, Alternatives to Platelet and RBC Transfusions, New Hemostatic Agents, Tx Practices for Children with Cancer, and Relevance of Cold Platelets and WB to the Bleeding Oncology Patient.
Hematology
This leading text reflects both the new direction and explosive growth of the field of hematology. Edited and written by practitioners who are the leaders in the field, the book covers basic scientific foundations of hematology while focusing on its clinical aspects. This edition has been thoroughly updated and includes ten new chapters on cellular biology, haploidentical transplantation, hematologic manifestations of parasitic diseases, and more. The table of contents itself has been thoroughly revised to reflect the rapidly changing nature of the molecular and cellular areas of the specialty. Over 1,000 vivid images, now all presented in full color for the first time, include a collection of detailed photomicrographs in every chapter, selected by a hematopathology image consultant. What's more, this Expert Consult Premium Edition includes access to the complete contents of the book online, fully searchable and updated quarterly by Dr. Hoffman himself. - Publisher.
Blood Banking and Transfusion Medicine
Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belo...
