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Given the evolution of cerebrospinal testing (CSF) testing methods, the near future is certain to see an explosion of new CSF analysis methodologies. Broad-based and extensively illustrated, Cerebrospinal Fluid in Clinical Practice provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. It examines the alterations of the composition of CSF in relation to diseases and disorders of the nervous system, emphasizing the findings that are useful in clinical practice. This expansive reference is perfect regardless of your level of experience in central nervous system diseases. Provides in-depth cov...
Examining meningitis mainly from a bacterial perspective, but also including an overview of viral, fungal and chronic meningitis, this book describes the anatomy of the meninges and clinical signs and symptoms of meningitis. Individual organisms that cause meningitis worldwide are dealt with in specific chapters, describing in detail how these pathogens interact with the human host at both a molecular and cellular level, providing a thorough understanding of bacterial virulence factors and host cell response.
This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small in...
The Third Edition of this definitive reference provides comprehensive guidelines on the diagnosis, treatment, and prevention of every infectious disease seen in current clinical practice. More than 300 world-class practitioners detail the full range of clinical infections, microorganisms, diagnostic tests, and antimicrobial therapies. Coverage includes chapters on surgical infections written by preeminent surgeons and up-to-the-minute information on HIV infection. A comprehensive antimicrobial drugs section includes tables that provide at-a-glance prescribing information. New Third Edition chapters cover bioterrorism, hospital infections, emerging infections, human herpesvirus-8, West Nile virus, food safety, linezolid and quinupristin/dalfopristin, molecular diagnostics, and diagnostic significance of nonspecific laboratory abnormalities.
Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and psychosocial profile, which often modify the clinical expression of neurologic and other diseases. In addition, ethnic, cultural, and economic factors are frequently overlooked in dealing with health problems of women, even though they undoubtedly have a strong influence on the clinical course of the illness. The second edition of Neurolo...
A clinically oriented, user-friendly text on the diagnosis and treatment of infectious diseases for practising clinicians, students and residents.
Tumor immunotherapy has now shown its promise for many, its disappointments and failings for others. Going forward, brain tumor patients can both benefit and contribute. Tumor immunotherapy is steadily progressing. As experience accumulates, it is important to consider its generality. The reviews herein emphasize the brain’s place among other tumor sites. Two major topics are addressed. THE SITE: WHAT CAN WE EXPECT FROM IMMUNOTHERAPY WHEN THE TARGET IS IN THE BRAIN? Experience with immunotherapy for different targets in the brain, including tumor and also pathogens, is reviewed. Long-standing assumptions are confronted. The potential for beneficial responses is stressed. BRAIN TUMOR IMMUNOTHERAPY: WHAT HAVE WE LEARNED SO FAR? Clinical experience with brain tumor immunotherapy, from a variety of centers, is reviewed. Primary tumors, emphasizing glioblastoma, and brain metastases are each considered.
This volume is the first in a planned series of thematic volumes for Advances in Virus Research. It covers the etiology, pathogenetic mechanisms, and clincial consequences of human neurotropic viruses. Buchmeier is a virologist, Campbell an immunologist, and both are extremely well known in their fields. - Numerous illustrations including colour - Knowledgeable discussion of the potential role of viral infections in teratogenic and developmental disorders - Frank discussion of the role of stress in disease - Behavioural consequences of chronic CNS infection
Ethnicity, Identity, and the Development of Nationalism in Iran investigates the ways in which Armenian minorities in Iran encountered Iranian nationalism and participated in its development over the course of the twentieth century. Based primarily on oral interviews, archival documents, memoirs, memorabilia, and photographs, the book examines the lives of a group of Armenian Iranians—a truck driver, an army officer, a parliamentary representative, a civil servant, and a scout leader—and explores the personal conflicts and paradoxes attendant upon their layered allegiances and compound identities. In documenting individual experiences in Iranian industry, military, government, education, and community organizations, the five social biographies detail the various roles of elites and nonelites in the development of Iranian nationalism and reveal the multiple forces that shape the processes of identity formation. Yaghoubian combines these portraits with a theoretical grounding to answer recurring pivotal questions about how nationalism evolves, why it is appealing, what broad forces and daily activities shape and sustain it, and the role of ethnicity in its development.