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Cuando el 21 de julio de 1588 el gran proyecto naval de Felipe II zarpó de A Coruña para invadir Inglaterra con una flota de 130 navíos y 30.000 hombres, la Armada Invencible inició su singladura hacia la leyenda. Pero, ¿dónde encontró el yunque donde forjó su funesto destino? En la hermosa y feraz costa occidental de Irlanda. Un total de 24 barcos naufragaron y 6.000 hombres perdieron la vida en sus costas.Hoy, cuatro siglos después de esa tragedia marítima y humana, el halo mí-tico de la Invencible sigue perviviendo en la Isla Esmeralda, grabado a fuego en su toponimia: desde las rocas basálticas de la Calzada del Gigante, en el Ulster, hasta la península de Dingle, en el sureño Kerry. Una huella que también late en la memoria de las increíbles aventuras de náufragos como el capitán Francisco de Cuéllar, en el cabello y los ojos oscuros de los black Irish, en el oro español expuesto en los museos de la isla…Descubrir los paisajes, los personajes y las historias que forjaron esa leyenda es el horizonte de este libro, un viaje tintado de aventura, emoción y recuerdo.
Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze one’s own data.
SPAIN, 1937. Posted to the Aragonese front, Lieutenant Lluís Ruscalleda eschews the drunken antics of his comrades and goes in search of intrigue. But the lady of Castel de Olivo - a beautiful widow with a shadowy past - puts a high price on her affections. In Barcelona, Trini Milmany struggles to raise Lluís' son on her own, letters from the front her only solace. With bombs falling as fast as the city's morale, she leaves to winter with Lluís' brigade on a quiet section of the line. But even on 'dead' fronts the guns do not stay silent for long. Trini's decision will put her family's fate in the hands of Juli Soleràs, old friend and traitor of easy conscience, a philosopher-cynic locked in an eternal struggle with himself. Joan Sales, a combatant in the civil war, distilled his experiences into a timeless story of thwarted love, lost youth and crushed illusions. A thrilling epic that has drawn comparison with the work of Dostoevsky and Stendhal, Uncertain Glory is a homegrown counterpart to classics such as Homage to Catalonia and For Whom the Bell Tolls.
In the past, neo-tribalism in a Western context has been feared as leading to blindness or irrationality. In today's business world, tribalism represents a conscious separation of the individual ego for the good of the community. This is the key to understanding the success of the most innovative businesses in the 21st century.
This book provides case studies and general views of the main processes involved in the ecosystem shifts occurring in the high mountains and analyses the implications for nature conservation. Case studies from the Pyrenees are preponderant, with a comprehensive set of mountain ranges surrounded by highly populated lowland areas also being considered. The introductory and closing chapters will summarise the main challenges that nature conservation may face in mountain areas under the environmental shifting conditions. Further chapters put forward approaches from environmental geography, functional ecology, biogeography, and paleoenvironmental reconstructions. Organisms from microbes to large carnivores, and ecosystems from lakes to forest will be considered. This interdisciplinary book will appeal to researchers in mountain ecosystems, students and nature professionals. This book is open access under a CC BY license.
This is the first of its kind in its topical coverage of the developments and prospects of Islamic finance education at Western higher education. Intended to establish itself as a unique reference for academics and researchers this book gives an insight into ethics and values in curricula development at business schools and in finance departments.
Aims to increase awareness about the specific circumstances of LGBT (lesbian, gay, bisexual, and transgender) diversity. Based on a wide array of literature this volume provides a global vision of this reality, explaining the evolution of homosexuality during history and reasons why it has been considered a sin, an illness and a crime.
Treedom is an exploration of Japan's most well-known treehouse builder Takashi Kobayashi. Takahashi, who has been featured in the New York Times and on Animal Planet's Treehouse Masters, as well as many television programs, newspapers, and magazines in Japan, examines being an outcast in a rigid society of rules and conformity and finding salvation in the trees. Treedom, filled with photography, poetry, and Takashi's personal accounts of treehouse building, describes how treehouse living is not just a lifestyle but a philosophy.
The coronary circulation is unique in that it is responsible for maintaining adequate oxygen and substrate delivery to the organ that generates the pressure needed to drive blood throughout the entire circulatory system. In the simplest terms, coronary blood flow is directly proportional to the arterial pressure gradient across the coronary vasculature and inversely proportional to coronary vascular resistance. However, myocardial perfusion is collectively regulated by a complex variety of mechanisms which include: (1) extravascular compressive forces; (2) diastolic time fraction; (3) coronary perfusion pressure; (4) myocardial metabolism (local metabolic factors); (5) endothelial-derived su...