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Advances in Host Genetics and microbiome in lifestyle-related phenotypes
Advances in Host Genetics and Microbiome in Lifestyle-Related Phenotypes, Volume 111 explores the recent discoveries in the interaction between Host Genetics-Microbiome and lifestyle-related phenotypes regarding precision nutrition, physical activity, sports performance, circadian rhythm, sleep, and rest. Chapters in this release include Techniques, procedures, and applications in host Genetic analysis, Techniques, procedures, and applications in Microbiome analysis, Human adaptations to diet: biological and cultural coevolution, Impact of Evolution on Lifestyle in Microbiome, Nutrition and host Genetics: nutrigenetics, Nutrition and Microbiome: microbiome nutrition, Genomic predictors of physical activity and athletic performance, physical activity and Microbiome, Microbiome and Host Genetics in Circadian Rhythm, and more. Explores Host Genetics and Microbiome in Nutrition Delves into nutrition, physical activity, sports performance, circadian rhythm, sleep, and rest Covers the impact of evolution on lifestyle
The Quintessence of Basic and Clinical Research and Scientific Publishing
The book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clini...
Bioinformatics and Human Genomics Research
Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.
Geotechnical Engineering in the XXI Century: Lessons learned and future challenges
The first Pan-American Conference on Soil Mechanics and Geotechnical Engineering (PCSMGE) was held in Mexico in 1959. Every 4 years since then, PCSMGE has brought together the geotechnical engineering community from all over the world to discuss the problems, solutions and future challenges facing this engineering sector. Sixty years after the first conference, the 2019 edition returns to Mexico. This book, Geotechnical Engineering in the XXI Century: Lessons learned and future challenges, presents the proceedings of the XVI Pan-American Conference on Soil Mechanics and Geotechnical Engineering (XVI PCSMGE), held in Cancun, Mexico, from 17 – 20 November 2019. Of the 393 full papers submitt...
Concussion
Topic editor Dr Zetterberger is a co-founder of Brain Biomarker Solutions in Gothenburg AB, a GU Ventures-based platform company at the University of Gothenburg. All other topic editors declare no competing interests with regards to the Research Topic subject.
Genome Plasticity in Health and Disease
Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors, non-coding RNAs, telomere dynamics and RNA editing. Later chapters explore disease relevance for cancer, as well as cardiovascular, neuropsychiatric, inflammatory, and endocrine disease, and associated pathways for drug discovery. - Examines the role of genome plasticity across a range of disease types, from cardiovascular disease, to cancer and neuropsychiatric disorders - Adopts an interdisciplinary approach, with expert contributions across the spectrum of basic science and disease relevance to drug discovery
Genomic Medicine in Emerging Economies
Originally thought to be available only to the world's wealthiest nations, genomic medicine has developed into a broad range of clinical methods and technologies whose concrete applications are also revolutionizing health systems in many of the world's resource-limited nations. Genomic Medicine in Emerging Economies: Genomics for Every Nation provides in-depth analysis and key examples of the implementation of medical genomics in low-income nations across the globe, demonstrating how this advancing medical science has already transformed health systems and led to improved patient care in Indonesian, Chilean, Malaysian, Argentinian, Chinese, Sri Lankan, and Colombian populations among others....
Manual Skills, Handedness, and the Organization of Language in the Brain
Whereas the cerebral specialization for skilled manual actions (praxis) seems closely linked to dominance for language, with both functions left lateralized in the vast majority of humans, the neural correlates of hand preference are still less well understood. Indeed, as a combination of inherited and non-inherited genomic factors (i.e., direct parental and concealed environmental contributions), handedness – in contrast to language – is less likely to have strong genetic indices and clearly lateralized functional organization. What about eye dominance, unimanual and bimanual object manipulation, and gestures, or attentional systems and the related egocentric or allocentric coding of sp...
Governing the military
Governing the military combines the study of governance, democratisation, and policymaking to explore how military politics have unfolded since the return to democracy in Chile. The book offers timely research to understand the rocky road to overcome the civil-military tension of the 1990s and the challenges presented by novel security demands in the twenty-first century, including the militarisation of urban crime and pandemics, and its consequences on human rights. The book will also introduce the reader to failed policies, lack of attention to governance, and decaying democratic practices. The volume examines eight themes considered fundamental to understand the modern governance of the armed forces: the state of civil-military relations, political transition and military subordination, roles and missions, military effectiveness, fiscal spending, inter-agency challenges, international engagements, and transparency and corruption.
Research on Emotion and Learning: Contributions from Latin America
Latin America has increased its share of world scientific publications by nearly twofold during the last two decades (approximately from 2 to 4%). Despite this positive trend, the scholarly impact of scientific research produced in the region - measured in terms of citation rate - remains low. Two interrelated factors that contribute to this situation is that most research groups tend to work in isolation or in local sporadic collaboration, and results are often published in journals that are not indexed in major citation databases (e.g., SCOPUS, or Web of Science). Ultimately, part of Latin American high-quality research seems to remain hidden from the rest of the world. Over the last decad...
