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Mathematical and Statistical Modeling for Emerging and Re-emerging Infectious Diseases
The contributions by epidemic modeling experts describe how mathematical models and statistical forecasting are created to capture the most important aspects of an emerging epidemic.Readers will discover a broad range of approaches to address questions, such as Can we control Ebola via ring vaccination strategies? How quickly should we detect Ebola cases to ensure epidemic control? What is the likelihood that an Ebola epidemic in West Africa leads to secondary outbreaks in other parts of the world? When does it matter to incorporate the role of disease-induced mortality on epidemic models? What is the role of behavior changes on Ebola dynamics? How can we better understand the control of cho...
An Introduction to Undergraduate Research in Computational and Mathematical Biology
Speaking directly to the growing importance of research experience in undergraduate mathematics programs, this volume offers suggestions for undergraduate-appropriate research projects in mathematical and computational biology for students and their faculty mentors. The aim of each chapter is twofold: for faculty, to alleviate the challenges of identifying accessible topics and advising students through the research process; for students, to provide sufficient background, additional references, and context to excite students in these areas and to enable them to successfully undertake these problems in their research. Some of the topics discussed include: • Oscillatory behaviors present in ...
The Domestic and International Impacts of the 2009-H1N1 Influenza A Pandemic
In March and early April 2009, a new, swine-origin 2009-H1N1 influenza A virus emerged in Mexico and the United States. During the first few weeks of surveillance, the virus spread by human-to-human transmission worldwide to over 30 countries. On June 11, 2009, the World Health Organization (WHO) raised the worldwide pandemic alert level to Phase 6 in response to the ongoing global spread of the novel influenza A (H1N1) virus. By October 30, 2009, the H1N1 influenza A had spread to 191 countries and resulted in 5,700 fatalities. A national emergency was declared in the United States and the swine flu joined SARS and the avian flu as pandemics of the 21st century. Vaccination is currently ava...
The HLA FactsBook
The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the h...
Reducing Suicide
Every year, about 30,000 people die by suicide in the U.S., and some 650,000 receive emergency treatment after a suicide attempt. Often, those most at risk are the least able to access professional help. Reducing Suicide provides a blueprint for addressing this tragic and costly problem: how we can build an appropriate infrastructure, conduct needed research, and improve our ability to recognize suicide risk and effectively intervene. Rich in data, the book also strikes an intensely personal chord, featuring compelling quotes about people's experience with suicide. The book explores the factors that raise a person's risk of suicide: psychological and biological factors including substance ab...
The Flu Pandemic of 1918-1919
Within the framework of a global political and sanitarian crisis that broke out in March 2020, this book proposes a new contemporary look at the great pandemic of the 20th century, the Spanish flu of 1918-1919. Based on its impact in Spain, the book offers a comparative and transatlantic perspective focused on the political and cultural impact of the pandemic in Europe and Latin America. The book focuses on three aspects: the overwhelming presence of influenza between 1918 and 1920, its oblivion and its political and cultural traces in the interwar decades and even more, and its reappearance in the face of the COVID-19. These three aspects are interconnected through a comparative analysis of the crisis of liberalism and democracy of the 1920s and 1930s and the current populist wave that is affecting the world. As such, this book is of great value to those interested in social and medical history across Europe and Latin America through offering a fresh outlook on the effects of the pandemic of the 20th century in the wake of the COVID pandemic that swept across the world.
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