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This new volume of the book series Advances in Anatomy, Embryology and Cell Biology provides a complete and exhaustive overview of the morphofunctional organization of the mammalian carotid body, a polymodal chemosensory organ responsible for the maintenance of blood gas homeostasis. The authors review the state of the art of the neurochemical anatomy of carotid body ́s cell populations with a special reference to their structural and neurochemical plasticity. The essential role of this organ in the generation, progression and maintenance of cardiorespiratory and metabolic diseases in humans and other mammals is presented. Finally, the book summarizes current knowledge on the stem cell niche in the mammalian carotid body and discusses its contribution to replacement cell therapy and other potential applications in translational research. This book represents an essential reading for physiologists, anatomists, cell, and developmental biologists, as well as physicians, veterinarians, and biomedical researchers.
This book provides a comprehensive overview of the multifaceted field of protease in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers working to identify targets for drug development. Multidisciplinary in scope, the book bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research. Proteases represent one o...
This volume details histochemical techniques for the detection of specific molecules or metabolic processes, both at light and electron microscopy. Chapters are divided into seven sections covering Vital histochemistry, Carbohydrate histochemistry, Protein histochemistry, Lipid histochemistry, Nuclear histochemistry, Plant histochemistry and Histochemistry for Nanoscience. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. The volume also contains three discursive chapters on Histochemistry in advanced cytometry, Lectins and Detection of molecules in plant cell walls by fluorescence microscopy. Authoritative and cutting-edge, Histochemistry of Single Molecules: Methods and Protocols, Second Edition aims to be a useful practical guide for researchers to help further their study in this field.
The authors of the most cited neuroscience publication, The Rat Brain in Stereotaxic Coordinates, have written this introductory textbook for neuroscience students. The text is clear and concise, and offers an excellent introduction to the essential concepts of neuroscience. - Based on contemporary neuroscience research rather than old-style medical school neuroanatomy - Thorough treatment of motor and sensory systems - A detailed chapter on human cerebral cortex - The neuroscience of consciousness, memory, emotion, brain injury, and mental illness - A comprehensive chapter on brain development - A summary of the techniques of brain research - A detailed glossary of neuroscience terms - Illu...
In this volume, Marichela Sepe explores the preservation, reconstruction and enhancement of cultural heritage and place identity. She outlines the history of the concept of placemaking, and sets out the range of different methods of analysis and assessment that are used to help pin down the nature of place identity.
This monograph sheds new light on pulmonary sensory receptors. Diving into the pulmonary microenvironment, the book focuses on the role of pulmonary neuroepithelial bodies (NEBs) as potential receptors and effectors, able to store and release neurotransmitters. It explores NEBs as potential stem cell niche and highlights the multidisciplinary approach taken to identify and study NEBs, including functional morphological investigation, live cell imaging, genetic models, and laser microdissection combined with gene expression analysis. Complexly organized NEBs are an integral part of the intrapulmonary airway epithelium of all air-breathing vertebrates. For decades a quest has been going on to ...
Ancient alchemy : the elements through the ages - Inner alchemy : elemental symbols and the psyche - Somatic alchemy - Elemental movement - Embodying the elements.
The Routledge Handbook of Language and Metaphor provides a comprehensive overview of state-of-the-art interdisciplinary research on metaphor and language, and maps out future directions of research and practice in a variety of contexts in this field.
"What is Fat Activism and why is it important? Charlotte Cooper, a fat activist with around 30 years experience, answers this question by lifting the lid on a previously unexplored social movement. Fat Activism: A Radical Social Movement is a rare insider's view of fat people speaking about their lives and politics on their own terms. It is part of a new wave of accessible, accountable and rigorous work emerging through Research Justice and the Para-Academy"--Page 4 of cover.