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Breast Surgical Techniques and Interdisciplinary Management
This comprehensive manual on breast disease deals with all aspects of the surgical management of both benign and malignant disease. The chapters are written by leading experts, clearly illustrated with line drawings, clinical photos and diagnostic radiology images. Breast Surgery is divided into sections following the patterns of patient management from diagnosis through treatment and reconstruction. Part One, "Fundamentals", addresses common aspects of working with breast cancer patients and understanding the members of the breast cancer team. Part Two is an overview of "Biologic Principles". Parts Three, Four, and Five review "The Initial Evaluation", "Common Presenting Problems", and "Dia...
Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors
An essential element in the development and functional integrity of all organisms is intercellular communication. This is achieved by the secretion of soluble messenger molecules which subsequently interact with receptor-effector pathways in the responsive cells. Hormones are traditionally defined as chemical messengers synthesized by endocrine glands. Unlike hormones produced by endocrine glands, growth factors are hormone-related substances produced by many tissues and play an important role in controlling growth and development. While the exact physiological roles of growth factors have yet to be elucidated, they play important roles in the regulation of cellular proliferation and/or diff...
Current Cancer Therapeutics
The updated Fourth Edition of Current Cancer Therapeutics offers contributions by by more than 60 renowned authors. The book provides an insightful guide to the overwhelming influx of new information and knowledge on an array of cancer types, as well as protocols for treatment and supportive care. Cutting-edge information, along with with a variety of professionally prepared tables and charts, makes this an unparalleled resource for all healthcare professionals.
The Breast E-Book
The Breast: Comprehensive Management of Benign and Malignant Diseases, 4th Edition, by Kirby I. Bland, MD, and Edward M. Copeland, III, MD, is a surgical reference that offers the most comprehensive, up-to-date resource on the diagnosis and management of, and rehabilitation following, surgery for benign and malignant diseases of the breast. With its multidisciplinary approach, sweeping updates, new contributors, and authoritative guidance, you’ll have exactly what you need to inspire patient confidence and provide the best possible outcomes. Features multidisciplinary advice from experts in surgery, radiation and medical oncology, pathology, molecular biology, pharmacokinetics, and genetic...
Endocrinology of Breast Cancer
A cutting-edge review of how derangements in the hormonal and growth factor mechanisms controlling normal mammary development lead to breast cancer. Drawing on the multidisciplinary expertise of leading authorities, the book highlights the roles of oncogenes and tumor suppressor genes, spelling out the importance of autocrine/paracrine loops (e.g., stromal epithelial interactions) in supporting breast cancer cell proliferation and the progression to hormone independence. The book's many prominent contributors also illuminate significant recent advances in the biochemistry and physiology of hormone receptors and review the state-of -the-art in the endocrine therapy of breast cancer. Endocrinology of Breast Cancer provides a unique integrated overview of the most significant basic and clinical developments concerning the hormonal aspects of breast cancer.
EGFR Signaling Networks in Cancer Therapy
The epidermal gro wth factor (EGF ) receptor and its downstream signal transduction networks have been implicated in the ontology and maintenance of tumor tissues, which has motivated the discovery and development of molecularly targeted anti-EGF receptor therapies. Over decades of study, the EGF receptor structure, its ligand binding domains, the physical biochemistry underlying its intrinsic tyrosine kinase catalytic function and the modular interactions with SH2, PTB, and SH3 domain containing signaling adaptor p- teins required for signal transduction, have been extensively dissected. Not only is the EGF receptor the nexus of many streams of information, but it also forms one part of a c...
Stocktake analysis of the agriculture sector in Solomon Islands
This report assesses activities in the agriculture sector in the Solomon Islands – including activities funded by development partners and the private sector, as well as activities across subsectors and export-oriented production – in order to identify policy activities and current status of key agricultural indicators. It also provides information to inform a strategic sectoral plan, which will include gaps and opportunities for future development and sectoral growth. The stocktake was designed to identify key constraints and opportunities, and to inform the government, particularly the Ministry of Agriculture and Livestock (MAL) in further developing strategic direction and assist them to capitalize on the support of development partners.
The NIH Record
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Michiganensian
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