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This volume brings together contributions exploring the mutual relationships between genetics, markets, societies, and identities in genetics and genomics. It draws upon the recent transdisciplinary debate on how socio-cultural factors influence understandings of ‘genetics2.0' and shows how individual and collective identities are challenged or reinforced by cultural meanings and practices of genetics. This book will become a standard reference for everyone seeking to make sense of the controversies and shifts in the field of genetics in the second decade of the twenty-first century.
Pteridine and folate research has long been recognized as important for many biological processes, such as amino acid metabolism, nucleic acid synthesis, neurotransmitter synthesis, cancer, cardiovascular function, and growth and development of essentially all living organisms. Defects in synthesis, metabolism and/or nutritional availability of these compounds have been implicated as major causes of common disease processes, e.g. cancer, inflammatory disorders, cardiovascular disorders, neurological diseases, autoimmune processes, and birth defects. Since pteridine and folate biology uses concepts and experimental techniques drawn from all of these disciplines, the breadth of this volume is its great strength, bringing together researchers from a wide variety of fields including biochemistry, chemistry, physics, biophysics, genetics, microbiology, cell and molecular biology, virology, immunology, cancer, neurobiology and medicine. This volume should be a valuable and unique reference work for scientists with interests in these areas as well as those seeking up to date information.
These papers are the proceedings of the International Symposium on the Chemistry and Biology of Pteridines and Folates. The book brings together contributions from some 250 scientists from chemistry, biochemistry, biology, pharmacology, and medicine to present and discuss recent advances in this expanding field.
This book is a comprehensive, empirically-grounded exploration of the relationship between bioethics, culture, and the perspective of being affected. It provides a new outlook on how complex “bioethical” issues become questions of everyday life. The authors focus on two contexts, genetic testing and end-of-life care, to locate and demonstrate emerging themes of responsibility, such as self-responsibility, responsibility for kin, and the responsibility of society. Within these themes, the duty to know versus the right not to know one's genetic fate (in the context of genetic testing), or the sanctity of life versus self-determination (in the context of end of life care) are identified as ...
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In recent times, the phrase ’personalised medicine’ has become the symbol of medical progress and a label for better health care in the future. However, a controversial debate has developed around whether these promises of better, more personal and more cost-efficient medicine are realistic. This book brings together leading researchers from across Europe and North America, from both normative and empirical disciplines, who take a more critical view of the often encountered hype associated with personalised medicine. Partially drawing on a four year collaborative research project funded by the German Ministry for Education and Research, the book presents a multidisciplinary debate on the current state of research on the ethical, legal and social implications of personalised medicine. At a time when future health care is a topic of much discussion, this book provides valuable policy recommendations for the way forward. This study will be of interest to researchers from various disciplines including philosophy, bioethics, law and social sciences.
This book investigates the iconic architectural cultural spaces of the contemporary cityscape as engines of regeneration. Promising much to their fading locales, these spaces locate culture in the space where production once ruled in order to revitalise post-industrial urban provinces. With close attention to four sites across the UK, Urban Constellations engages with the work of Walter Benjamin and Jean Baudrillard, to read these spaces and in so doing, offer a critical intervention into the theory and experience of contemporary cityscapes.
This book explores the intertwining of politics and ontology, shedding light on the ways in which, as our ability to investigate, regulate, appropriate, ‘enhance’ and destroy material reality have developed, so new social scientific accounts of nature and our relationship with it have emerged, together with new forms of power. Engaging with cutting-edge social theory and elaborating on the thought of Foucault, Heidegger, Adorno and Agamben, the author demonstrates that the convergence of ontology with politics is not simply an intellectual endeavour of growing import, but also a governmental practice which builds upon neoliberal programmes, the renewed accumulation of capital and the development of technosciences in areas such as climate change, geoengineering and biotechnology.