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Chemistry and Biology of Pteridines and Folates
The pteridines in their multitude of forms fulfill many roles in nature ranging from pigments to cofactors for numerous redox and one-carbon transfer reactions. This extraordinary diversity of function is unified by the unique chemistry of the pteridine heterocycle. The International Symposium on the Chemistry and Biology of Pteridines and Folates is a forum for presenting recent and exciting advances in this expanding field. In of ideas results that has often stimulated bringing together various disciplines, a synergy fresh approaches to major problems. The Tenth International Symposium held at Orange Beach, Alabama, March 21-23, 1993, proved no exception by providing new insights into fola...
Chemistry and Biology of Pteridines and Folates
Pteridine and folate research has long been recognized as important for many biological processes, such as amino acid metabolism, nucleic acid synthesis, neurotransmitter synthesis, cancer, cardiovascular function, and growth and development of essentially all living organisms. Defects in synthesis, metabolism and/or nutritional availability of these compounds have been implicated as major causes of common disease processes, e.g. cancer, inflammatory disorders, cardiovascular disorders, neurological diseases, autoimmune processes, and birth defects. Since pteridine and folate biology uses concepts and experimental techniques drawn from all of these disciplines, the breadth of this volume is its great strength, bringing together researchers from a wide variety of fields including biochemistry, chemistry, physics, biophysics, genetics, microbiology, cell and molecular biology, virology, immunology, cancer, neurobiology and medicine. This volume should be a valuable and unique reference work for scientists with interests in these areas as well as those seeking up to date information.
The A3 Workbook
Encouraging efficiency, clarity, and disciplined thinking, A3 Problem Solving identifies a problem, describes the objective, and summarizes fact finding and action steps, all on a single A3-sized piece of paper. This approach provides all employees at all levels with a method to quickly identify a problem, analyze it to root cause, select appropria
Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products
In order to make further progress in elucidating the mechanism of NOS catalysis it will be essential to throw light on the interaction between the enzyme and its substrate. An understanding of the catalytic site will also assist the development of therapeutically important NOS inhibitors. In particular. it will be useful to uncover any differences that exist between the substrate binding sites of the three NOS isozymes which might be exploited for the development of isoform selective NOS inhibitors. A comparison of NOS to other Arg-binding proteins has shown no significant sequence homology (159). Moreover, the lack of a 3D structure and absence of significant sequence homology between the N...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Progress in Iron Research
The 4th International Conference on Hemochromatosis and the 11th International Conference on Iron and Iron Proteins took place in Jerusalem on April 27 -30 and on May 2 -7 1993, respectively. The first, a clinical meeting, and the second, a forum designed primarily for basic scientists. Both meetings are held regularly on alter nate years and represent probably the most important forum for the exchange of information in iron research. The present volume "Progress in Iron Research" is based on a selection of presentations delivered at these meetings. However, this volume represents much more than a publication of conference proceedings. It offers a comprehensive state-of-the-art review on mos...
Forschung fördern
Durch Kulturbegegnung, internationalen Wissenschaftsaustausch und interkulturelle Vergleiche sind Grenzen nationaler und westlicher Forschungsansätze deutlich geworden. In diesem Buch werden Beispiele für nachhaltige Wirkungen einer unkonventionellen Wissenschaftsförderung durch weitsichtiges Unternehmer- und Mäzenatentum vorgestellt. Deutsche und japanische Wissenschaftler behandeln in rechtswissenschaftlichen, soziologischen, historischen und psychologischen Beiträgen die kulturellen Bedingungen und Besonderheiten von Lebensqualität, Zufriedenheit und Glück. Sie zeigen, wie wirtschaftliches Handeln über ökonomische Interessen hinaus mit zivilgesellschaftlichem Engagement verbunden wird oder Wissenschaft wiederum auch durch ökonomische Interessen beeinträchtigt werden kann.
