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Oral Drug Delivery for Modified Release Formulations
  • Language: en
  • Pages: 516

Oral Drug Delivery for Modified Release Formulations

ORAL DRUG DELIVERY FOR MODIFIED RELEASE FORMULATIONS Provides pharmaceutical development scientists with a detailed reference guide for the development of MR formulations Oral Drug Delivery for Modified Release Formulations is an up-to-date review of the key aspects of oral absorption from modified-release (MR) dosage forms. This edited volume provides in-depth coverage of the physiological factors that influence drug release and of the design and evaluation of MR formulations. Divided into three sections, the book begins by describing the gastrointestinal tract (GIT) and detailing the conditions and absorption processes occurring in the GIT that determine a formulation’s oral bioavailabil...

Innovative Processing Technologies for Foods with Bioactive Compounds
  • Language: en
  • Pages: 326

Innovative Processing Technologies for Foods with Bioactive Compounds

  • Type: Book
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  • Published: 2016-08-05
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  • Publisher: CRC Press

Natural foods, like fruits and vegetables, represent the simplest form of functional foods and provide excellent sources of functional compounds. Maximizing opportunities to make use of and incorporate these compounds requires special processing. Fortunately, technologies available to produce food with enhanced active compounds have advanced significantly over the last few years. This book covers the fundamentals as well as the innovations made during the last few years on the emerging technologies used in the development of food with bioactive compounds.

Edmunds' Pharmacology for the Primary Care Provider - E-Book
  • Language: en
  • Pages: 866

Edmunds' Pharmacology for the Primary Care Provider - E-Book

Approx.860 pagesApprox.860 pages - NEW! Thoroughly updated content reflects the latest drug information and current thinking on pharmacologic management. - NEW macro- and chapter-level organization is based on body systems rather than drug classes, for better coverage of the medications prescribed for the health problems affecting specific body systems. - NEW and UNIQUE! Chapter format begins with an overview of anatomy, physiology, and disease processes — as opposed to drug classes or drug types — and then follows the World Health Organization's Process for Rational Prescribing, using a six-step approach to drug selection and discussing first-, second-, and third-line treatments for eac...

Drug Delivery Approaches
  • Language: en
  • Pages: 466

Drug Delivery Approaches

Explore this comprehensive discussion of the application of physiologically- and physicochemical-based models to guide drug delivery edited by leading experts in the field Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics delivers a thorough discussion of drug delivery options to achieve target profiles and approaches as defined by physical and pharmacokinetic models. The book offers an overview of drug absorption and physiological models, chapters on oral delivery routes with a focus on both PBPK and multiple dosage form options. It also provides an explanation of the pharmacokinetics of the formulation of drugs delivered by systemic transdermal routes. The d...

Fundamentals of Drug Delivery
  • Language: en
  • Pages: 580

Fundamentals of Drug Delivery

A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the deve...

Oral Drug Absorption
  • Language: en
  • Pages: 432

Oral Drug Absorption

  • Type: Book
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  • Published: 2016-04-19
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  • Publisher: CRC Press

Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an

Pulmonary Drug Delivery
  • Language: en
  • Pages: 392

Pulmonary Drug Delivery

Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation ...

Molecules and Medicine
  • Language: en
  • Pages: 272

Molecules and Medicine

Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.

Microneedle-mediated Transdermal and Intradermal Drug Delivery
  • Language: en
  • Pages: 238

Microneedle-mediated Transdermal and Intradermal Drug Delivery

Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and...

Vaccinology
  • Language: en
  • Pages: 552

Vaccinology

Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human application Includes evaluation of vaccine efficacy and safety Details clinical trial design, including regulatory requirements Discusses the emerging field of active cellular immunotherapy Vaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.