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A decade ago, oestrogen-containing hormone therapy was viewed as a promising strategy for the prevention and treatment of dementia and age-related cognitive decline. However, treatment trials in women with Alzheimer's disease showed that oestrogens did not reverse cognitive impairment, and clinical trials in healthy older women indicated that oestrogens did not prevent cognitive decline. The Women's Health Initiative Memory Study trial even suggested an increased risk of dementia with treatment late in life. What happened? How are we to understand these findings? What are the implications for middle-aged and older women? What about testosterone, and what about men? And where do we go from here? This book brings together world-renowned experts in basic and clinical research on sex steroids, aging, and cognition to integrate existing findings with emerging new data, and offer challenging hypotheses on these key issues.
• Presents evidence-based design examples from a real-world demonstration house • Illustrated with colour images and graphics • Focus on residential housing whereas most other books focus on products or care homes
Basic and clinical research on sex steroids, ageing, and cognition to integrate existing findings with emerging data.
Menopause is a significant event in a woman’s life as is generally considered as an indicator for senescence in women. Evidence suggests that menopause results in many psychological and postmenopausal health problems, such as anxiety, osteoporosis, cardiovascular disease, metabolic disorder and others. Menopausal symptoms and associated disorders are of great importance for public health as they influence the quality of life of affected individuals. Therefore proper management of menopause will definitely contribute to healthy aging and the overall well-being of women. This e-book reviews recent progress in the research and management of menopause and associated health problems. It provide...
Demographers, economists, sociologists and anthropologists analyse the implications of population ageing for family and community welfare and public policy.
The progressive growth in the number of older adults worldwide has led to a modification of the current healthcare scenario and a parallel increase in the use of public resources. In this book, we propose a conceptual framework within which aging, frailty, and care are analyzed through the lens of complexity medicine. Therefore, we present a multidimensional perspective that takes into account biomedical, (neuro)psychological, and socio-ecological vulnerability. The theses presented are the result of an inductive approach, based on many years of experience in the field, which has made it possible to identify strategies for frailty recognition and effective responses even in complicated clinical settings. The book is intended to be a tool of concrete and easy consultation, rich in reflections and suggestions.
Positive Ageing and Learning from Centenarians evaluates the mechanisms of positive ageing in a uniquely interdisciplinary way to explore the question of how we age and how some people age successfully. Drawing together the findings of recognised longevity researchers from around the world, the book applies an integrated vision to educational and social aspects of human ageing. It examines research into centenarians, and considers most of the disciplines related to longevity and healthy aging and aspects such as education, psychology, philosophy, anthropology, demography, sociology, economics as well as those related to nutrition and biological factors of longevity. The book examines how the...
"A book about the influence of estrogens on memory would have been unthinkable as recently as 30 years ago. Although a few small studies in the late 1970's reported a beneficial effect of estrogens on memory in human women (Hackman and Galbraith, 1976; Fedor-Freybergh, 1977), examination of the role of estrogens in memory did not truly capture more widespread attention until the pioneering work of Barbara Sherwin and colleagues in 1988 and beyond. In her initial paper, Sherwin showed that bilateral removal of the ovaries (aka surgical menopause) led to impaired short-term and long-term memory, whereas treatment of surgically menopausal women with estradiol alone, testosterone alone, or estra...