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Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach
  • Language: en
  • Pages: 250

Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach

Loss of muscle mass and increased fibrosis characterize both sarcopenia of aging and muscular dystrophy. Research is increasingly showing that these two conditions also share several pathophysiological mechanisms, including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and abnormal regulation of signaling and stress response pathways. This Research Topic will cover several mechanisms involved in aging and dystrophic sarcopenia and explore the therapeutic potential of various strategies for intervention.

Dietary Protein and Muscle in Aging People
  • Language: en
  • Pages: 161

Dietary Protein and Muscle in Aging People

  • Type: Book
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  • Published: 2019-02-14
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  • Publisher: MDPI

This book is a printed edition of the Special Issue "Dietary Protein and Muscle in Aging People" that was published in Nutrients

Geriatric Medicine
  • Language: en
  • Pages: 1634

Geriatric Medicine

None

Frailty
  • Language: en
  • Pages: 403

Frailty

None

Muscle Homeostasis and Regeneration
  • Language: en
  • Pages: 500

Muscle Homeostasis and Regeneration

  • Type: Book
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  • Published: 2020-11-20
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  • Publisher: MDPI

The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.

Dementia, Frailty and Aging
  • Language: en
  • Pages: 121

Dementia, Frailty and Aging

The number of older subjects is rapidly increasingly worldwide. As a consequence, the nature of clinical conditions is also changing. Traditional medicine and models of care have been based on the evaluation and treatment of single and usually acute conditions occurring in relatively young individuals. Today, the usual clinical manifestation of diseases is characterized by multiple and often chronic conditions affecting older people. In this scenario, frailty and dementia have been triggering special interest both in research and clinical settings due to their high prevalence, impact on the individual’s quality of life, and consequences for public health worldwide. These conditions aptly r...

Assessment and Treatment of Sarcopenia and Frailty in the Setting of Personalized Internal Medicine
  • Language: en
  • Pages: 150

Assessment and Treatment of Sarcopenia and Frailty in the Setting of Personalized Internal Medicine

The recognition and implementation of personalized internal medicine is of the utmost importance for physicians, nurses, dieticians and other healthcare professionals engaged in clinics. The assessment of sarcopenia and frailty, in middle-aged patients, as an embodiment of treatment personalization, is essential in settings of acute and chronic disease, both in the hospital and in ambulatory settings. This book describes various practical tools for the assessment of sarcopenia and frailty, reviews relevant findings from the current professional literature, and suggests treatment modifications for frail patients.

Oxford Textbook of Geriatric Medicine
  • Language: en
  • Pages: 1393

Oxford Textbook of Geriatric Medicine

The third edition of the definitive international reference book on all aspects of the medical care of older persons will provide every physician involved in the care of older patients with a comprehensive resource on all the clinical problems they are likely to encounter, as well as on related psychological, philosophical, and social issues.

Active and Healthy Ageing: A Multifocal Novel Trend to Increase Resilience in Elderly
  • Language: en
  • Pages: 118
Nutrition in Older Adults, An Issue of Clinics in Geriatric Medicine
  • Language: en
  • Pages: 177

Nutrition in Older Adults, An Issue of Clinics in Geriatric Medicine

This issue of Clinics in Geriatric Medicine is devoted to Nutrition in Older Adults. Guest Editor John E. Morley, MD has assembled a group of expert authors to review the following topics: Anorexia of Aging; Protein and Older Persons; Screening for Malnutrition in Older People; Obesity and Aging; Vitamins; Sarcopenia; Diabetes: Nutrition and Exercise; Frailty, Exercise and Nutrition; Dehydration; Cholesterol and Older Persons; Cognition and Nutrition; and Gastric Emptying in the Elderly.