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This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.
This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson's disease. Throughout the book, the DOR system as a target for drug development will be discussed.
The Delta Receptor spans current research in delta receptor biology, pharmacology, physiology, and chemistry to identify, advance, and inspire the development of novel drug candidates. It demonstrates the potential significance and impact of the delta receptor in the therapy and treatment of medical conditions such as pain, gastrointestinal disorders, bladder dysfunction, and depression, as well as heart attack prevention. This reference examines the pathophysiological functions and mechanisms of receptor-selective drugs. Documenting key advances in the field, The Delta Receptor represents the most comprehensive and up-to-date studies on receptor applications currently available.
A Doody's Core Title for 2023! The landmark pharmacology reference—updated to reflect the latest research and developments in the field For more than 50 years, Goodman & Gilman’s: The Pharmacological Basis of Therapeutics has represented the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. The text's careful balance of basic science and clinical applications has guided thousands of health care practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing and treating disease. This Fourteenth Edition includes five new chapters, 600+ illustrations, and important ...
Includes data for the Ann Arbor, Dearborn, and Flint campuses.
Jan. 2003- : "7 directories in 1: section 1: alphabetical section; section 2: business section; section 3: telephone number section; section 4: street guide; section 5: map section; section 6: movers & shakers; section 7: demographic summary."
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