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Almost four decades of innovative and intensive research on Alzheimer’s disease (AD) have brought major advances in our understanding of its pathogenesis, improved tools for diagnosis, and strategies for its treatment. This research has helped build a solid foundation of knowledge in the neurosciences and biological basis of AD and AD-related neurological disorders. Scientific background and insightful hypotheses are of major relevance in order to approach to an effective therapy for this devastating disease. Current Hypotheses and Research Milestones in Alzheimer's Disease contains 20 seminal chapters by authors with varying views on the neuroanatomical, neuropathological, neuropsychological, neurological, and molecular aspects of AD. These chapters grew out of “Current Hypothesis on Alzheimer’s Disease”, held in Viña del Mar, Chile, in November of 2007. Participants included the world’s leading Alzheimer’s researchers, whose work has illuminated AD investigations during the past few decades. Students, academics and medical professionals will find this text an invaluable addition to the study of this important subject.
This book discusses in detail the different hypothesis and experimental evidence regarding the neurobiological mechanisms involved in neurodegenerative pathology, with an emphasis in Alzheimer's and Parkinson's disease. Since there are many hypotheses for neurodegenerative diseases, there is a real need for a comprehensive view, allowing for integration of the different views for the pathogenic mechanisms of the disease.
A 64-page concise handbook for professional and student writers, arrangers, copyists, editors or proofreaders -- anyone working with music manuscripts. Included are sections on general music notation, shorthand notation, proofreading, terms and type, choral/vocal music, instrumental scores and parts, pop and keyboard music, plus a special section with specifics for engravers.
Las experiencias relatadas sobre los meses de confinamiento, reunidas en este libro, serán comprensibles para todo aquel que ha vivido las circunstancias de esta pandemia global. Se trata de una marca muy profunda que hemos recibido de manera colectiva y, por lo tanto, las lectoras y lectores de este libro serán capaces de sentirse cómplices de estos relatos.