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This volume presents contributions from leading European scholars, considering Paul and his Jewish context and considering the implications for contemporary Jewish-Christian dialogue.
The protection mode of most available vaccines is based on antibody responses. Since efficient immune responses to many pathogens rely on activating all arms of the immune system, traditional vaccine development does not provide efficient protection against many diseases. Novel vaccination strategies need to allow presentation of antigens that activate the full array of the immune response in the right composition and should prevent pathogen entry by mobilizing the mucosal immune response. New technological advances optimize the immunogenicity of 'live' and sub-unit vaccines. This book offers an interdisciplinary overview on research and future strategies for rational vaccine design based on recent developments in molecular biology and immunology. It covers new aspects of the immunological interplay between prokaryotic and eukaryotic systems as well as achievements in the development of novel vaccine candidates. Chapters on edible vaccines, on vaccines against bioterror agents and on economical and safety aspects of novel vaccine development round off this title.
This set of selected papers of Klingenberg covers some of the important mathematical aspects of Riemannian Geometry, Closed Geodesics, Geometric Algebra, Classical Differential Geometry and Foundations of Geometry of Klingenberg. Of significance were his contributions to Riemannian Geometry in the Large which opened a new area in Global Riemannian Geometry. He also introduced the Hilbert manifold of closed curves of class H1 on a Riemannian manifold. In connection with his work in closed geodesics, he became interested in the properties of the geodesic flow. Classical results from dynamical systems became useful tools for the study of closed geodesics. He was also credited for drawing closer together Riemannian Geometry and Hamiltonian systems, which had developed separately since the time of H Poincaré.Besides publishing research papers, Klingenberg also wrote a dozen books and lecture notes, among which is the important reference work “Riemannsche Geometrie im Groβen”.
Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine.
Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.
These two fragments of novels, Ingeborg Bachmann's only untranslated works of fiction, were intended to follow the widely acclaimed Malina in a cycle to be entitled Todesarten, or Ways of Dying. Although Bachmann died before completing them, The Book of Franza and Requiem for Fanny Goldmann stand on their own, continuing Bachmann's tradition of using language to confront the disease plaguing human relationships. Through the tales of two women in postwar Austria, Bachmann explores the ways of dying inflicted upon the living from outside and from within, through history, politics, religion, family, gender relations, and the self.Bachmann's allegiance to the twin muses of memory and history, as...